跳到主要內容區塊
:::醫學研究部 > 公開資訊 > 基礎醫學研究科 > 基礎醫學研究室 > 糖尿病及動脈硬化實驗室

研究著作

引用 (2)
更新日期 2022/10/11 15:00:05
點閱 1194
Publications: (* corresponding author) (2018-2022)
期刊可連結

 
1 Lee WJ, Lin KH, Wang JS, Sheu WHH, Shen CC, Yang CN, Wu SM#, Shen LW, Shu-Hua Lee SH, Lai DW, Lan KL, Tung CW, Liu SH#, Sheu ML*. Aryl hydrocarbon receptor deficiency augments dysregulated microangiogenesis and diabetic retinopathy. Biomed Pharmacother. 2022 Sep; 155:113725. (SCI)
2 Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, …, Lee, WJ, …, et al. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. Am J Hum Genet. 2022; 109(8):1366-87. (SCI)
3 Lee WJ, Han-Ni Chuang#, ChenYM, Liang KW, Tung H, Chen JP, Lee IT, Wang JS, Lin CH, Lin HJ, Sheu WHH, and Lee WL*, Hsiao TH*. Familial hypercholesterolemia genetic variations and long-term cardiovascular outcomes in patients with hypercholesterolemia who underwent coronary angiography. Genes (Basel). 2021 Sep; 12(9): 1413. (SCI)
4 Lin TH, Lee WL, Lee WJ# (Share corresponding author), Sheu WHH, LiaoYC and Liang KW*. Dyslipidemia, not inflammatory markers or adipokines, contribute significantly to a higher SYNTAX score in stable coronary artery disease (from the Taichung CAD study). Acta Cardiol Sin. 2021 May; 37(3): 232-8. (SCI)
5 Sheu WHH, Lin KH, Wang JS, Lai DW, Lee WJ, Lin FY, Chen CH, Yeh HY, Wu SM, Shen CC, Lee MR, Liu SH, Sheu ML*. The therapeutic potential of tumor progression locus 2 inhibition on diabetic vasculopathy through the blockage of the inflammasome complex. Arterioscler, Thromb, Vasc Biol. 2021; 41 (1):e46–e62. (SCI)
6 Chu# EPF, Cho# CHH, Lee WJ# (Share first author), Lee IT, Cheng IF, Kuo TC, Chen RY, Sheu WHH, ShenCN*. Generation of three induced pluripotent stem cell lines from type 2 diabetic patients with ocular complications. Stem Cell Res. 2020; 49:102109. (SCI)
7 Surendran P, Karthikeyan S, Chen L, Prins BP, Stewart ID, Foley CN, …, Lee WJ, …, et al. Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals. Nat Genet. 2020; 52(12):1314-32. (SCI)
8 Bick AG, Weinstock JS, Nandakumar SK, Fulco CP, Bao EL, Zekavat SM., …, Sheu W. H, …, Lee WJ, Chang, K., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Inherited causes of clonal haematopoiesis in 97,691 whole genomes. Nature. 2020 Oct; 586(7831):763-8. (SCI)
9 Li X, Li Z, Zhou H, Gaynor SM, Liu Y, Chen H, …, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium (Lee WJ, Sheu WHH). Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nature Genetics . 2020 Sep; 52(9):969-83. (SCI)
10 Liang KW*, Lee WJ, Lee IT, Lee WL, Wang JS, Wu JP, Sheu WH. Subjects with microvascular angina have longer GT repeats polymorphism in the haem oxygenase-1 gene promoter. Biomarkers. 2020 Mar; 25(2):144-8. (SCI)
11 Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, …, Lee WJ, …, Celedón JC. NHLBI TOPMed Consortium. De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. Proc Natl Acad Sci . 2020 Feb 4;117(5):2560-9.. (SCI)
12 Liao CC, Sheu WH, Lin SY, Lee WJ, Lee IT*. The relationship between abdominal body composition and metabolic syndrome after a weight reduction program in adult men with obesity. Diabetes Metab Syndr Obes. 2020 Jan; 13:1-8. (SCI)
13 Kachroo P, Hecker J, Chawes BL, Ahluwalia TS, Cho MH, Qiao D, …, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium. (Lee WJ, Sheu WHH). Whole genome sequencing identifies CRISPLD2 as a lung function gene in children with asthma. Chest. 2019 Dec; 156(6):1068-79. (SCI)
14 Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N , Gandin I, …, Lee WJ, …, et al.. Associations of autozygosity with a broad range of human phenotypes. Nat Commun. 2019 Oct; 10(1):4957. (SCI)
15 Sung YJ, Winkler TW, de las Fuentes L, Bentley AR, Brown MR, Kraja AT, …, Lee WJ, …, et al. A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Hum Mol Genet. 2019 Aug; 28(15):2615-33. (SCI)
16 Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, …, Lee WJ, …, et al..  Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body fat distribution. Nat Genet. 2019 Mar; 51(3):452-69. (SCI)
17 Kraja AT, Liu C, Fetterman JL, Graff M, Have, CT Gu C, …, Lee WJ, …, et al.. Associations of mitochondrial and nuclear mitochondrial variants and genes with seven metabolic traits. Am J Hum Genet. 2019 Jan; 104(1):112-38. (SCI)
18 Wang JS, Lee WJ, Lee IT, Lin SY, Lee WL, Liang KW, Sheu WH*. Association between serum adipsin levels and insulin resistance in subjects with various degrees of glucose intolerance. J Endocr Soc. 2018 Dec; 3(2):403-10. (SCI)
19 Liao WL, Chang CT, Chen CC, Lee WJ, Lin SY, Liao HY, …, et al.. Urinary proteomics for early diagnosis of diabetic nephropathy in Taiwanese. J Clin Med. 2018 Dec; 7(12):483. (SCI)
20 Wang JS, Lee WJ, Lee IT, Lin SY, Lee WL, Liang KW, Lin SJ, Sheu WH*. Negative association between serum aryl hydrocarbon receptor concentrations and β-cell function in patients with no history of diabetes undergoing coronary angiography. J Diabetes. 2018 Dec; 10(12):958-64. (SCI)
21 Liang KW, Lee WJ (Co-first author), Lee IT, Lin SY, Wang JS, Lee WL*, Sheu WH*. Regaining body weight after weight reduction further increases pulse wave velocity in obese men with metabolic syndrome. Medicine (Baltimore). 2018 Oct; 97(40):e12730. (SCI)
22 Fu CP, Sheu WH, Lee WL, Lee WJ, Wang JS, and, Lee IT.* Two-hour post-challenge hyperglycemia, but not fasting plasma glucose, associated with severity of coronary artery disease in patients with angina. PLoS One. 2018 Aug; 13(8):e0202280. (SCI)
23 Wang JS, Sheu WH, Lee WJ, Lee IT, Lin SY, Lee WL, Liang KW, Lin SJ*. Levels of serum high mobility group box 1 were independently associated with cardiovascular risk in patients undergoing coronary angiography. Clin Chim Acta. 2018 Aug; 483:130-4. (SCI)
24 Natarajan P, Peloso GM, Zekavat SM, Montasser M, Ganna A, Chaffin M, …, NHLBI TOPMed Lipids Working Group. (Lee WJ, Sheu WHH). Deep coverage whole genome sequences and plasma lipoprotein (a) in individuals of European and African ancestries. Nat Commun. 2018 Jul; 9(1):2606. (SCI)
25 Li YH, Sheu WH, Lee WJ, Lee IT, Lin SY, Lee WL, Liang KW, Lin SJ, Wang JS*. Testing for HbA1c, in addition to oral glucose tolerance test, in screening for abnormal glucose regulation helps to reveal patients with early β-cell function impairment. Clin Chem Lab Med. 2018 Jul; 56(8):1345-52. (SCI)
26 Gusarova V, O’Dushlaine C, Teslovich TM, …, Lee WJ, …, et al.. Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes. Nat Commun. 2018 Jun; 9(1):2252. (SCI)
27 Li YH, Sheu WH, Lee WJ, Wang JS, Fu CP, Liang KW, Lee IT*. Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease‒ a cross-sectional study. Sci Rep. 2018 May; 8(1):7378. (SCI)
28 Lee IT, Sheu WH, Lee WJ, Chen DY. Serum brain-derived neurotrophic factor predicting reduction in pulse pressure after a one-hour rest in nurses working night shifts. Sci Rep. 2018 Apr; 8(1):5485. (SCI)
29 Sung YJ, Winkler TW, de las Fuentes L, Bentley AR, Brown MR, Kraja AT, …, Lee WJ, …, et al.. A large-scale multi-ancestry genome-wide study accounting for smoking behavior identifies multiple significant loci for blood pressure. Am J Hum Genet. 2018 Mar; 102(3):375-400. (SCI)
30 Lee IT, Chen CH, Wang JS, Fu CP, Lee WJ, Liang KW, Lin SY, Sheu WH.* The association between brain-derived neurotrophic factor and central pulse pressure after an oral glucose tolerance test. Clin Chim Acta. 2018 Jan; 476:1-8. (SCI)
 
 
回頂端