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研究著作

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更新日期 2023/9/26 11:16:40
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研究著作
Publications: (* corresponding author)
1 S. H. Li, Qian, Y. H. Chen, H.I. Lu, H.T. Tsai, H. Lyu, R. Yang, C.H. Chen* (2022) Targeting MYO1B impairs tumorigenesis and chemoresistance via inhibiting the SNAI2/cyclin D1 signaling in esophageal squamous cell carcinoma. J Cell Physiol. (Accept) (IF=6.513; Ranking=10/81 (Q1); Category: Physiology) (SCI)
2 Y.H. Chen, C.H. Chen, C.Y. Chien, Y.Y. Su, S.D. Luo and S.H. Li (2022) JMJD3 suppresses tumor progression in oral tongue squamous cell carcinoma patients receiving surgical resection. PeerJ. Jul 13;10:e13759 (IF=3.061; Ranking=33/73 (Q2); Category: Multidisciplinary Sciences) (SCI)
3 S.D. Luo, H.T. Tsai, C.F. Hwang, T.J. Chiu, S.H. Li, Y.L. Hsu, C.C. Hsiao, C.H. Chen* (2022) Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis. J Exp Clin Cancer Res. Jul 1; 41(1):215 (IF=12.658; Ranking=24/245 (Q1); Category: Oncology) (SCI)
4 H.W. Lin, T.J. Shen, P.Y. Chen, T.C. Chen, J.H. Yeh, S.C. Tsou, C.Y. Lai, C.H. Chen*, Y.Y. Chang* (2022) Particulate matter 2.5 exposure induces epithelial-mesenchymal transition via PI3K/AKT/mTOR pathway in human retinal pigment epithelial ARPE-19 cells. Biochem Biophys Res Commun. 617 (Pt 2), 11-17 (IF=3.322; Ranking=39/72 (Q3); Category: Biophysics) (SCI)
5 S.D. Luo, H.T. Tsai, T.J. Chiu, S.H. Li, Y.L. Hsu, L.J. Su, M.H. Tsai, C.Y. Lee, C.C. Hsiao*, C.H. Chen* (2022) Leptin silencing attenuates lipid accumulation through sterol regulatory element-binding protein 1 inhibition in nasopharyngeal carcinoma. Int J Mol Sci. 23(10), 5700 (IF=6.208; Ranking=69/296 (Q1); Category: Biochemistry & Molecular Biology) (SCI)
6 T.L. Huang, C.R. Chang, C.Y. Chien, G.K. Huang, Y.F. Chen, H.T. Tsai, Y.S. Lin, H. Lyu, F.M. Fang*, C.H. Chen* (2022) DRP1 contributes to head and neck cancer progression and induces glycolysis through modulated FOXM1/MMP12 axis. Mol Oncol. Mar 21;16(13):2585-2606 (IF=7.449; Ranking=51/245 (Q1); Category: Oncology) (SCI)
7 T.J. Chiu, Y.J. Chen, J. Lan, Y.Y. Chen, Y.C. Chen, S.W. Lin, H.T. Tsai, Y.S. Lin, C.C. Hsiao*, C.H. Chen* (2021) Downregulation of Notch3 links TIMP3 inhibition to suppress aggressive phenotypes of pancreatic ductal adenocarcinoma. Am J Cancer Res. Nov 15;11(11):5609-5624 (IF=5.942; Ranking=71/245 (Q2); Category: Oncology) (SCI)
8 C.Y. Wu, J.D. Liao, C.H. Chen, H. Lee, S. Wang, B. H. Liu, C.Y. Lee, P.L. Shao and E. Li (2021) Non-thermal reactive N2/He plasma exposure to inhibit epithelial head and neck tumor cells. Coatings Nov;11(11):1284 (IF=3.236; Ranking=9/19 (Q2); Category: Materials Science, Coatings & Films) (SCI)
9 Y.H. Chen, C.H. Chen, C.Y. Chien, Y.Y. Su, S.D. Luo, S.H. Li (2021) Overexpression of UTX promotes tumor progression in oral tongue squamous cell carcinoma patients receiving surgical resection: a case control study. BMC Cancer Sep 1;21(1):979 (IF=4.638; Ranking=109/245 (Q2); Category: Oncology) (SCI)
10 S.D. Luo, S.C. Wu, W.C. Chen, C.N. Wu, T.J. Chiu, Y.H. Yang, S.H. Li, F.M. Fang, T.L. Huang, C.C. Hsiao*, C.H. Chen* (2021) Low-dose aspirin confers a survival benefit in patients with pathological advanced-stage oral squamous cell carcinoma. Sci Rep. Aug 25;11(1):17161 (IF=4.996; Ranking=19/73 (Q2); Category: Multidisciplinary Sciences) (SCI)
11 W. Yang, C.H. Chen#, M. Jia, X. Xing, L. Gao, Z. Zhang, Z. Liu, B. Zeng, S.C. Jim Yeung, M.H. Lee, C. Cheng. (2021) Tumor-associated microbiota in esophageal squamous cell carcinoma. Front Cell Dev Biol. Feb 18;9:641270. (IF=6.081; Ranking=6/39 (Q1); Category: Developmental Biology) (SCI) co-first and co-corresponding author
12 D. Zheng, X. Hu, Y.S. Lin, C.H. Chen (2020) Tunable multi-resonance of terahertz metamaterial using split-disk resonators. AIP Advances. 10:025108 (IF=1.697; Ranking=120/161 (Q3); Category: Physics, Applied) (SCI)
13 J. Dai, R. Xu, Y.S. Lin, C.H. Chen (2020) Tunable electromagnetic characteristics of suspended nanodisk metasurface. Optics and Laser Technology. August; 128:106214 (IF=4.939; Ranking=20/101 (Q1); Category: Optics) (SCI)
14 Y. Wen, Z. Liang, Y.S. Lin, C.H. Chen (2020) Active modulation of polarization-sensitive infrared metamaterial. Optics Communications. 463:125489 (IF=2.335; Ranking=51/101 (Q3); Category: Optics) (SCI)
15 C.H. Chen, L.J. Su, H.T. Tsai, C.F. Hwang (2019) ELF-1 expression in nasopharyngeal carcinoma facilitates proliferation and metastasis of cancer cells via modulation of CCL2/CCR2 signaling. Cancer Manag Res. Jun 6; 11:5243-5254 (IF=3.602; Ranking=154/245 (Q3); Category: Oncology) (SCI)
16 C.H. Wang, P.W. Hung, C.W. Chiang, M Lombès, C.H. Chen, K.H. Lee, Y.C. Lo, M.H. Wu, W.C. Chang, D.Y. Lin (2019) Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation. Biochim Biophys Acta Mol Cell Res. Aug;1866(8):1282-1297 (IF=5.011; Ranking=110/296 (Q2); Category: Biochemistry & Molecular Biology) (SCI)
17 S.H. Li, H.I. Lu, Y.H. Chen, C.M. Lo, W.T. Huang, W.Y. Tien, Y.C. Lan, H.T. Tsai, C.H. Chen* (2019) JMJD3 expression is an independent prognosticator in patients with esophageal squamous cell carcinoma. Surgery May;165(5):946-952 (IF=4.348; Ranking=36/211 (Q1); Category: Surgery) (SCI)
18 S.H. Li, H.I. Lu, W.T. Huang, Y.H. Chen, C.M. Lo, Y.C. Lan, W.C. Lin, H.T. Tsai, C.H. Chen* (2018) An actin-binding protein ESPN is an independent prognosticator and regulates cell growth for esophageal squamous cell carcinoma. Cancer Cell International 2018;18:219 (IF=6.429; Ranking=63/245 (Q2); Category: Oncology) (SCI)
19 H.L. You, T.T. Liu, S.W. Weng, C.H. Chen, Y.C. Wei, H.L. Eng, W.T. Huang (2018) Association of IRS2 overexpression with disease progression in intrahepatic cholangiocarcinoma. Oncol Lett. Oct;16(4):5505-5511 (IF=3.111; Ranking=176/245 (Q3); Category: Oncology) (SCI)
20 T.J. Chiu, H.I. Lu, C.H. Chen, W.T. Huang, Y.M. Wang, W.C. Lin, S.H. Li. (2018) Osteopontin expression is associated with the poor prognosis in patients with locally advanced esophageal squamous cell carcinoma receiving preoperative chemoradiotherapy. Biomed Res Int. Apr 30;2018:9098215 (IF=3.246; Ranking=90/158 (Q2); Category: Biotechnology & Applied Microbiology) (SCI)
21 K.I. Lin, C.C. Lin, S.M. Kuo, J.C. Lai, YQ. Wang, H.L. You, M.L. Hsu, C.H. Chen*, L.Y. Shiu (2018) Carnosic acid impedes cell growth and enhances anticancer effects of carmustine and lomustine in melanoma. Biosci Rep. Jul 2;38(4). BSR 20180005 (IF=3.976; Ranking=165/296 (Q3); Category: Biochemistry & Molecular Biology) (SCI)
22 M.C. Ma, T.J. Chiu, H.I. Lu, W.T. Huang, C.M. Lo, W.Y. Tien, Y.C. Lan, Y.Y. Chen, C.H. Chen, S.H. Li (2018) SIRT1 overexpression is an independent prognosticator for patients with esophageal squamous cell carcinoma. J Cardiothorac Surg. Apr 10;13(1):25 (IF=1.522; Ranking=165/211 (Q4); Category: Surgery) (SCI)
23 S.H. Li, H.I. Lu, W.T. Huang, W.Y. Tien, Y.C. Lan, W.C. Lin, H.T. Tsai, C.H. Chen* (2018) The Prognostic Significance of Histone Demethylase UTX in Esophageal Squamous Cell Carcinoma. Int J Mol Sci. Jan 19;19(1). pii: E297 (IF=6.208; Ranking=69/296 (Q1); Category: Biochemistry & Molecular Biology) (SCI)
24 S.H. Li, C.Y. Chien, W.T. Huang, S.D. Luo, Y.Y. Su, W.Y. Tien, Y.C. Lan, C.H. Chen* (2017) Prognostic significance and function of mammalian target of rapamycin in tongue squamous cell carcinoma. Sci Rep. Aug 15;7(1):8178 (IF=4.996; Ranking=19/73 (Q2); Category: Multidisciplinary Sciences) (SCI)
25 C.Y. Tsai, Y.Y., Poon, C.H. Chen, S.H.H. Chan (2017) Anomalous baroreflex functionality inherent in floxed and Cre-Lox mice: an overlooked physiological phenotype. Am J Physiol Heart Circ Physiol. Oct 1;313(4):H700-H707 (IF=5.125; Ranking=15/81 (Q1); Category: Physiology) (SCI)
26 Y.Y. Su, C.H. Chen#, C.Y. Chien, W.C. Lin, W.T. Huang and S.H. Li (2017) Mitochondrial assembly receptor expression is an independent prognosticator for patients with oral tongue squamous cell carcinoma. J Renin-Angiotensin-Aldosterone Syst. Jul-Sep;18(3):1470320317717904 (IF=4.109; Ranking=29/67 (Q2); Category: Peripheral Vascular Disease) (SCI) #co-first author
27 C.H. Chen# and S.H. Li (2017) A novel therapeutic approach for esophageal squamous cell carcinoma: suppressor of cytokine signaling-1 gene therapy. J Thorac Dis. Jun;9(6):1446-1449 (IF=3.005; Ranking=45/65 (Q3); Category: Respiratory System) (SCI)
28 G.K. Huang, T.T. Liu, S.W. Weng, H.L. You, Y.C. Wei, C.H. Chen, H.L. Eng and W.T. Huang (2017) CUL4A overexpression as an independent adverse prognosticator in intrahepatic cholangiocarcinoma. BMC Cancer Jun; 17(1):395 (IF=4.638; Ranking=109/245 (Q2); Category: Oncology) (SCI)
29 C.H. Chen, H.T. Tsai, H.C. Chuang, L.Y. Shiu, L.J. Su, T.J. Chiu, S.D. Luo, F.M. Fang, C.C. Huang, and C.Y. Chien (2017) Metformin disrupts malignant behavior of oral squamous cell carcinoma via a novel signaling involving Late SV40 factor/Aurora-A. Sci Rep. May; 7(1):1358 (IF=4.996; Ranking=19/73 (Q2); Category: Multidisciplinary Sciences) (SCI)
30 H.L. You, S.J. Chang, H.R. Yu, C.C. Li, C.H. Chen, and W.T. Liao (2017) Simultaneous detection of respiratory syncytial virus and human metapneumovirus by one-step multiplex real-time RT-PCR in patients with respiratory symptoms. BMC Pediatr. Mar; 17(1):89 (IF=2.567; Ranking=68/130 (Q3); Category: Pediatrics) (SCI)
31 C.H. Chen#, M.F. Chen, S. Joseph Huang, C.Y. Huang, H.K. Wang, W.C. Hsieh, C.H. Huang, L.F. Liu and L.Y. Shiu (2017) Saikosaponin a Induces Apoptosis through Mitochondria-Dependent Pathway in Hepatic Stellate Cells. Am J Chin Med. Feb; 45(2):351-368 (IF=6.005; Ranking=2/30 (Q1); Category: Integrative & Complementary Medicine) (SCI)
32 C.H. Chen, H.I. Lu, Y.M. Wang, Y.H. Chen, C.M. Lo, W.T. Huang and S.H. Li (2017) Areca nut is associated with younger age of diagnosis, poor chemoradiotherapy response, and shorter overall survival in esophageal squamous cell carcinoma. PLoS One Feb; 12(2):e0172752 (IF=3.752; Ranking=29/73 (Q2); Category: Multidisciplinary Sciences) (SCI)
33 S.H. Li, H.I. Lu, Y.W. Alice Chang, W.T. Huang, W.C. Lin, C.C. Lee, W.Y. Tien, Y.C. Lan, H.T. Tsai and C.H. Chen* (2016) Angiotensin II type I receptor (AT1R) is an independent prognosticator of esophageal squamous cell carcinoma and promotes cells proliferation via mTOR activation. Oncotarget Oct; 7(41):67150-67165.
34 M.F. Chen, S. Joseph Huang, C.C. Huang, P.S. Liu, K.I. Lin, C.W. Liu, W.C. Hsieh, L.Y. Shiu and C.H. Chen* (2016) Saikosaponin d induces cell death through caspase-3-dependent, caspase-3-independent and mitochondrial pathways in mammalian hepatic stellate cells. BMC Cancer Jul; 16:532 (IF=4.638; Ranking=109/245 (Q2); Category: Oncology) (SCI)
35 S.H. Li, W.C Lin, T.L. Huang, C.H. Chen, T.J. Chiu, F.M. Fang, W.T. Huang, C.M. Hsu, S.D. Luo, C.C. Lai, Y.Y. Su, H.C. Chuang and C.Y. Chien (2016) Significance of mTOR in patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil. Head Neck-J Sci Spec Head Neck Apr; 38 Suppl 1:E844-52 (IF=3.821; Ranking=6/43 (Q1); Category: Otorhinolaryngology) (SCI)
36 A. Tseng, C.H. Yang, C.H. Chen, C.H. Chen, S.L. Hsu, M.H. Lee, H.C. Lee and L.J. Su (2016) An in vivo molecular response analysis of colorectal cancer treated with Astragalus membraneaceus extract. Oncol Rep. Feb; 35(2):659-668 (IF=4.136; Ranking=128/245 (Q3); Category: Oncology) (SCI)
37 C.H. Chen, H.C. Chuang, Y.T. Lin, F.M. Fang, C.C. Huang, C.M. Chen and C.Y. Chien (2016) Circulating CD105 shows significant impact in patients of oral cancer and promotes malignancy of cancer cells via CCL20. Tumor Biol Feb; 37(2):1995-2005
38 Y.H. Chen, C.H. Huang, H.I. Lu, C.H. Chen, W.T. Huang, M.J. Hsieh, K.M. Rau, Y.W. Alice Chang, W.C. Lin and S.H. Li (2015) Prognostic impact of renin-angiotensin system blockade in esophageal squamous cell carcinoma. J Renin-Angiotensin-Aldosterone Syst. Dec; 16(4):1185-1192 (IF=4.109; Ranking=29/67 (Q2); Category: Peripheral Vascular Disease) (SCI)
39 S.D. Luo, Y.J. Chen, C.T. Liu, K.M. Rau, Y.C. Chen, H.T. Tsai, C.H. Chen* and T.J. Chiu (2015) Osteopontin involves cisplatin resistance and poor prognosis in oral squamous cell carcinoma. Biomed Res Int Sep; 2015; 2015:508587:1-13 (IF=3.246; Ranking=91/139 (Q3); Category: Medicine, Research & Experimental) (SCI)
40 C.P. Yang, C.W. Chiang, C.H. Chen, Y.C. Lee, M.H. Wu, Y.H. Tsou, Y.S. Yang, W.C. Chang and D.Y. Lin (2015) Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58). J Biomed Sci. May; 22(1):33 (IF=12.771; Ranking=11/139 (Q1); Category: Medicine, Research & Experimental) (SCI)
41 C.H. Chen  *, Y.W. Alice Chang, S.H. Li, H.T. Tsai, L.Y. Shiu, L.J. Su, W.L. Wang, T.J. Chiu, S.D. Luo, T.L. Huang and C.Y. Chien (2015) Suppression of Aurora-A-FLJ10540 signaling axis prohibits the malignant state of head and neck cancer. Mol Cancer Apr; 14(1):83 (IF=41.444; Ranking=7/245 (Q1); Category: Oncology) (SCI) Highly accessed; #first and *corresponding author
42 S.H. Li, C.H. Chen, H.I. Lu, W.T. Huang, W.Y. Tien, Y.C. Lan, C.C. Lee, Y.H. Chen, H.Y. Huang, Y.W. Alice Chang and W.C. Lin (2015) Phosphorylated p70S6K expression is an independent prognosticator for patients with esophageal squamous cell carcinoma. Surgery Mar; 157(3):570-80 (IF=4.348; Ranking=36/211 (Q1); Category: Surgery) (SCI)
43 C.Y. Tsai, C.H. Chen, Y.W. Alice Chang, Y.H. Julie Chan and H.H. Samuel Chan (2015) Upregulation of FLJ10540, a PI3K-association protein, in rostral ventrolateral medulla impairs brain stem cardiovascular regulation during mevinphos intoxication. Biochem Pharmacol. Jan; 93(1):34-41 (IF=6.1; Ranking=46/279 (Q1); Category: Pharmacology & Pharmacy) (SCI) #co-first author
44 Y.W. Alice Chang, C.H. Faith Li, C.W. Huang, C.C. Julie Wu, K.Y. Dai, C.H. Chen, S.H. Li, C.H. Su and R.W. Wu (2014) Interplay between brain stem angiotensins and monocyte chemoattractant protein-1 as a novel mechanism for pressor response after ischemic stroke. Neurobiol Dis. Aug; 71:292-304 (IF=7.046; Ranking=43/274 (Q1); Category: Neurosciences) (SCI)
45 C.Y. Chien, H.T. Tsai, L.J. Su, H.C. Chuang, L.Y. Shiu, C.C. Huang, F.M. Fang, MD, C.C. Yu, H.T. Su and C.H. Chen* (2014) Aurora-A signaling is activated in advanced stage of squamous cell carcinoma of head and neck cancer and requires osteopontin to stimulate invasive behavior. Oncotarget Apr; 5(8):2243-62
46 C.C. Hsu, C.H. Chen, T.I. Hsu, J.J. Hung, J.L. Ko, B. Zhang, Y.C. Lee, H.K. Chen, W.C. Chang and D.Y. Lin (2014) The 58-kDa microspherule protein (MSP58) represses human telomerase reverse transcriptase (hTERT) gene expression and cell proliferation by interacting with telomerase transcriptional element-interacting factor (TEIF). Biochim Biophys Acta-Mol Cell Res. Mar; 1843(3):565-79 (IF=5.011; Ranking=93/194 (Q2); Category: Cell Biology) (SCI)
47 H.H. Huang, C.H. Chen#, S.C. Huang, C.H. Yang and C.F. Hwang (2014) Expression of 14-3-3 sigma, cyclin-dependent kinases 2 and 4, p16, and Epstein–Barr nuclear antigen 1 in nasopharyngeal carcinoma. J Laryngol Otol. Feb; 128(2):134-41 (IF=2.187; Ranking=27/43 (Q3); Category: Otorhinolaryngology) (SCI) #co-first author
48 T.J. Chiu, Y.J. Chen, K.M. Rau, C.H. Chen, C.Y. Chien, S.H. Li, H.T. Tsai and H.L. Eng (2013) Midkine neurite growth-promoting factor 2 expression as a potential prognostic marker of adjuvant therapy in head and neck squamous cell carcinoma. Biomarkers Dec; 18(8):687-98 (IF=2.663; Ranking=115/158 (Q3); Category: Biotechnology & Applied Microbiology) (SCI)
49 S.J. Chiou, C.H. Chen (2013) Decipher β2-microglobulin: Gain- or loss-of-function (a mini-review) Med. Sci. Monit. Basic Res. Oct; 19:271-3
50 M.F. Chen, C.C. Huang, P.S. Liu, C.H. Chen* and L.Y. Shiu (2013) Saikosaponin a and saikosaponin d inhibit proliferation and migratory activity of rat HSC-T6 cells. J Med Food Sep; 16(9):793-800 (IF=2.542; Ranking=45/63 (Q3); Category: Chemistry, Medicinal) (SCI) *co-corresponding author
51 C.Y. Chien, H.C. Chuang, C.H. Chen, F.M. Fang, W.C. Chen, C.C. Huang and H.Y. Huang (2013) The expression of activin receptor-like kinase 1 among patients with head and neck cancer. Otolaryngol Head Neck Surg. Jun; 148(6):965-973 (IF=5.591; Ranking=3/43 (Q1); Category: Otorhinolaryngology) (SCI)
52 C.H. Chen, H.C. Chuang, C.C. Huang, F.M. Fang, H.Y. Huang, H.T. Tasi, L.J. Su, L.Y. Shiu, Steve Leu and C. Y. Chien (2013) Overexpression of Rap-1A indicates a poor prognosis for oral cavity squamous cell carcinoma and promotes tumor cell invasion via Aurora-A modulation. Am J Pathol. Feb; 182:516-528 (IF=5.77; Ranking=12/77 (Q1); Category: Pathology) (SCI)
53 S.H. Li, E.Y. Huang, H.I. Lu, W.T. Huang, C.C. Yen, W.C. Huang and C.H. Chen* (2012) Phosphorylated mammalian target of rapamycin expression is associated with the response to chemoradiotherapy in patients with esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg. Dec; 144:1352-1359 (IF=6.439; Ranking=15/211 (Q1); Category: Surgery) (SCI)
54 C.Y. Chien, H.C. Chuang and C.H. Chen (2012) The side population of cancer stem-like cells in human oral cancer. Oral Oncol. Oct; 48(10):913-4 (IF=5.972; Ranking=6/92 (Q1); Category: Dentistry, Oral Surgery & Medicine) (SCI)
55 Y.W. Lin, C.F. Li, H.Y. Chen, C.Y. Yen, L.C. Lin, C.C. Huang, H.Y. Huang, P.C. Wu, C.H. Chen, S.C. Chen and M.H. Tai (2012) The expression and prognostic significance of hepatoma-derived growth factor in oral cancer. Oral Oncol. Jul; 48(7):629-35 (IF=5.972; Ranking=6/92 (Q1); Category: Dentistry, Oral Surgery & Medicine) (SCI)
56 L.J. Su, C.H. Yang, S.F. Huang, Y.L. Yuo, H.C. Hsieh, T.L. Tseng, C.H. Chen, S.L. Hsu and C.Y.F. Huang (2012) Evaluation of the Chinese medicinal herb, Graptopetalum paraguayense, as a therapeutic treatment for liver damage in rat models. Evid-Based Complement Altern Med. Jul; 2012:256561 (IF=2.65; Ranking=16/30 (Q3); Category: Integrative & Complementary Medicine) (SCI)
57 C.C. Hsu, Y.C. Lee, C.H. Chen, S.H. Yeh, C.C. Wu, T.Y. Wang, Y.N. Chen, L.Y. Hung, Y.W. Liu, H.K. Chen, Y.T. Hsiao, W.S. Wang, J.H. Tsou, Y.H. Tsou, M.H. Wu, W.C. Chang and D.Y. Lin (2012) 58-kDa microspherule protein (MSP58) is a novel brahma-related gene 1 (BRG1)-associated protein that modulates the p53-p21 senescence pathway. J Biol Chem. Jun; 287(27):22533-48 (IF=5.486; Ranking=94/296 (Q2); Category: Biochemistry & Molecular Biology) (SCI)
58 Y.T. Lin, H.C. Chuang, C.H. Chen, G.L. Armas, H.K. Chen, F.M. Fang, C.C. Huang and C.Y. Chien (2012) Clinical significance of erythropoietin receptor expression in oral squamous cell carcinoma. BMC Cancer May; 12:194 (IF=4.638; Ranking=109/245 (Q2); Category: Oncology) (SCI)
59 C.H. Chen, L.Y. Shiu, L.J. Su, C.Y.F. Huang, S.C. Huang, C.C. Huang, Y.F. Yin, W.S. Wang, H.T. Tasi, F.M. Fang, W.C. Chuang, H.C. Kang and C.F. Hwang (2012) FLJ10540 is associated with tumor progression in nasopharyngeal carcinomas and contributes to nasopharyngeal cell proliferation, and metastasis via osteopontin/CD44 pathway. J Transl Med. May; 10:93 (IF=8.459; Ranking=25/139 (Q1); Category: Medicine, Research & Experimental) (SCI) #co-first author
60 A.L. H. Tseng, F.H. Chung, H.C. Lee, L.C. Wu, C.H. Chen and L.J. Su (2012) Microarray analysis and establishment of drug screening platform using 5-fluorouracil resistance HCT116 colon cancer cells. Genomic Medicine, Biomarkers, and Health Science May; 4:21-2
61 C.F. Hwang, H.Y. Huang, C.H. Chen, C.Y. Chien, Y.C. Hsu, C.F. Li and F.M. Fang (2012) Enhancer of zeste homolog 2 overexpression in nasopharyngeal carcinoma: an independent poor prognosticator that enhances cell growth. Int J Radiat Oncol Biol Phys. Feb; 82(2):597-604 (IF=8.013; Ranking=45/245 (Q1); Category: Oncology) (SCI)
62 H.C. Chuang, F.M. Fang, C.C. Huang, H.Y. Huang, H.K. Chen, C.H. Chen and C.Y. Chien (2011) Clinical and pathological determinants in tonsil cancer. Head Neck-J Sci Spec Head Neck Dec; 33(12):1703-7 (IF=3.821; Ranking=6/43 (Q1); Category: Otorhinolaryngology) (SCI)
63 T.J. Chiu, C.H. Chen, C.Y. Chien, S.H. Li, H.T. Tsai and Y.J. Chen (2011) High ERCC1 expression predicts cisplatin-based chemotherapy resistance and poor outcome in unresectable squamous cell carcinoma of head and neck in a betel-chewing area. J Transl Med. Mar; 9:31 (IF=8.459; Ranking=25/139 (Q1); Category: Medicine, Research & Experimental) (SCI) #co-first author
64 H.C. Chuang, C.H. Chen#, C.C. Huang, F.M. Fang, H.T. Tsai and C.Y. Chien (2011) Reduced expression of TRF1 is associated with tumor progression and poor prognosis in oral squamous cell carcinoma. Exp Ther Med. Jan; 2(1):63-67 (IF=2.751; Ranking=105/139 (Q4); Category: Medicine, Research & Experimental) (SCI) #co-first author
65 C.F. Hwang, C.Y. Chien, S.C. Huang, Y.F. Yin, C.C. Huang, F.M. Fang, H.T. Tsai and C.H. Chen* (2010) Fibulin-3 is associated with tumour progression and a poor prognosis in nasopharyngeal carcinomas and inhibits cell migration and invasion via suppressed AKT activity. J Pathol. Dec; 222(4):367-79 (IF=9.883; Ranking=4/77 (Q1); Category: Pathology) (SCI)
66 J.N. Al-Swiahb, C.C. Huang, F.M. Fang, H.C. Chuang, H.Y. Huang, S.D. Luo, C.H. Chen, C.M. Chen and C.Y. Chien (2010) Prognostic impact of p16, p53, epidermal growth factor receptor, and human papillomavirus in oropharyngeal cancer in a betel nut-chewing area. JAMA Otolaryngol-Head Neck Surg. May; 136(5):502-8 (2013 Archives of Otolaryngology-Head & Neck Surgery title changes)
67 J.N. Al-Swiahb, C.H. Chen#, H.C. Chuang, F.M. Fang, H.T. Tsai and C.Y. Chien (2010) Clinical, pathological and molecular determinants in squamous cell carcinoma of the oral cavity. Future Oncol. May; 6(5):837-50 (IF=3.674; Ranking=149/245 (Q3); Category: Oncology) (SCI) #co-first author
68 J.M. Lai, C.Y. Huang and C.H. Chen* (2010) Using siRNA to uncover novel oncogenic signaling pathways. Methods Mol Biol. 623:231-42.
69 C.H. Chen, C.Y. Chien, C. C. Huang, H. C. Chuang, F. M. Fang, H. Y. Huang, C. M. Chen, H. L. Liu and C.Y. F Huang (2009) Expression of FLJ10540 is correlated with aggressiveness of oral cavity squamous cell carcinoma by stimulating cell migration and invasion through increased FOXM1 and MMP-2 activity. Oncogene Jul; 28(30):2723-37 (IF=8.756; Ranking=38/245 (Q1); Category: Oncology) (SCI)
70 M.T. Ko, C.Y. Su, S.C. Huang, C.H. Chen and C.F. Hwang (2009) Overexpression of cyclin E messenger ribonucleic acid in nasopharyngeal carcinoma correlates with poor prognosis. J Laryngol Otol. Mar; 123(a):1021-6 (IF=2.187; Ranking=27/43 (Q3); Category: Otorhinolaryngology) (SCI)
71 C.H. Chen, J.M. Lai, T.Y. Chou, C.Y. Chen, L.J. Su, Y.C. Lee, T.S. Cheng, Y.R. Hong, J. Whang-Peng, C.K. Chou, Y.C. Wu and C.Y. F. Huang (2009) VEGFA upregulates FLJ10540 and modulates migration and invasion of lung adenocarcinoma via PI3K/AKT pathway. PLoS One 4(4):e5052 (IF=3.752; Ranking=29/73 (Q2); Category: Multidisciplinary Sciences) (SCI)
72 C.Y. Chien, C.Y. Su, H.C. Chuang, F.M. Fang, H.Y. Huang, C.H. Chen, C.M. Chen and C.C. Huang (2009) Comprehensive study on the prognostic role of osteopontin expression in oral squamous cell carcinoma. Oral Oncol. Sep; 45(9):798-802 (IF=5.972; Ranking=6/92 (Q1); Category: Dentistry, Oral Surgery & Medicine) (SCI)
73 F.M. Fang, C.Y. Chien, C.F. Li, W.Y. Shiu, C.H. Chen and H.Y. Huang (2009) Effects of S-phase kinase-associated protein 2 expression on distant metastasis and survival in nasopharyngeal carcinoma patients. Int J Radiat Oncol Biol Phys. Jan; 73(1):202-7 (IF=8.013; Ranking=45/245 (Q1); Category: Oncology) (SCI)
74 C.H. Chen, C.Y. Su, H.C. Chuang, F.M. Fang, H.Y. Huang, C.M. Chen, C.C. Huang, S. J. Chiou and C.Y. Chien (2008) Overexpression of β2-microglobulin is associated with poor survival in patients with oral cavity squamous cell carcinoma and contributes to oral cancer cell migration and invasion. Br J Cancer 99:1453-1461 (IF=9.089; Ranking=37/245 (Q1); Category: Oncology) (SCI)
75 C.Y. Chien, C.Y. Su, H.C. Chuang, F.M. Fang, H.Y. Huang, C.M. Chen, C.H. Chen and C.C. Huang (2008) Angiopoietin-1 and -2 expression in recurrent squamous cell carcinoma of the oral cavity. J Surg Oncol. 97:273-277 (IF=2.885; Ranking=83/211 (Q2); Category: Surgery) (SCI)
76 C.Y. Chien, C.Y. Su, H.C. Chuang, F.M, Fang, H.Y. Huang, C.M. Chen, C.H. Chen and C.C. Huang (2008) Clinical significance of osteopontin expression in T1 and T2 tongue cancers. Head Neck-J Sci Spec Head Neck Jun; 30(6):776-81 (IF=3.821; Ranking=6/43 (Q1); Category: Otorhinolaryngology)  (SCI)
77 C.H. Chen, P.J. Lu, Y.C. Chen, S.L. Fu, S.F. Yeh, A.P. Tsou, K.J. Wu, C.Y. F. Huang and C.K. Chou (2007) FLJ10540-elicited cell transformation is through the activation of PI3-kinase/AKT pathway. Oncogene Jun 21; 26(29):4272-83 (IF=8.756; Ranking=38/245 (Q1); Category: Oncology) (SCI)
78 C.N. Hsu, J.M. Lai, C.H. Liu, H.H. Tseng, C.Y. Lin, K.T. Lin, H.H. Yeh, T.Y. Sung, W.L. Hsu, L.J. Su, S.A. Lee, C.H. Chen, G.C. Lee, D.T. Lee, Y.L. Shiue, C.W. Yeh, C.H. Chang, C.Y. Kao and C.Y. F. Huang (2007) Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (Encyclopedia of Hepatocellular Carcinoma genes Online). BMC Bioinformatics Feb 27; 8:66 (IF=3.307; Ranking=37/79 (Q2); Category: Biochemical Research Methods) (SCI)
79 C.W. Yang, J.Y. Su, A.P. Tsou, G.Y. Chau, H.L. Liu, C.H. Chen, C.Y. Chien and C.K. Chou (2005) Integrative genomics based identification of potential human hepatocarcinogenesis-associated cell cycle regulators: RHAMM as an example. Biochem Biophys Res Commun. 308(4):975-83 (IF=3.322; Ranking=39/72 (Q3); Category: Biophysics) (SCI)
80 C.H. Chen, S.L. Howng, T.S. Cheng, M.H. Chou, C.Y. Huang and Y.R. Hong (2003) Molecular characterization of human ninein protein: two distinct subdomains required for centrosomal targeting and regulating signals in cell cycle. Biochem Biophys Res Commun. 308(4):975-83 (IF=3.322; Ranking=39/72 (Q3); Category: Biophysics) (SCI)
81 S.L. Hwang, T.S. Cheng, C.H. Chen, Y.J. Sun, C.D. Hsiao and Y.R. Hong (2001) Boundary sequences of the NADPH oxidase p67 (phox) C-terminal SH3 domain play on its specificity. Biochem Biophys Res Commun. 289(1):97-102 (IF=3.322; Ranking=39/72 (Q3); Category: Biophysics) (SCI)
82 Y.R. Hong, C.H. Chen, M.H. Chuo, S.Y. Howng and S.L Howng (2000) Genomic organization and molecular characterization of the human ninein gene. Biochem. Biophys Res Commun. 279(3)989-95 (IF=3.322; Ranking=39/72 (Q3); Category: Biophysics) (SCI) (SCI)
83 Y.R. Hong, C.H. Chen, C.H. Chang, S.K. Wang, W.D. Sy, C.K. Chou and S.L. Howng (2000) Cloning and characterization of a novel human ninein protein that interacts with the glycogen synthase kinase 3β. Biochim. Biophys. Acta-Gene Regul. Mech. 1492(2-3):513-6.
84 C.H. Chen, S.L. Howng, S.L. Hwang, C.K. Chou, C.H. Liao and Y.R. Hong (2000) Differential expression of four human dynamin-like protein variants in brain tumors. DNA Cell Biol. 19(3):184-194 (IF=3.55; Ranking=87/175 (Q2); Category: Genetics & Heredity) (SCI)
85 C.H. Chen, S.L. Hwang, S.L. Howng, C.K. Chou and Y.R. Hong (2000) Three rat brain alternative splicing dynamin-like protein variants: interact with the glycogen synthase kinase 3β and act as a substrate. Biochem Biophys Res Commun. 268(3):893-898. (IF=3.322; Ranking=39/72 (Q3); Category: Biophysics) (SCI)
86 Y.R. Hong, C.H. Chen, D.S. Cheng, S.L. Howng and C.K. Chou (1998) Human dynamin-like protein interacts with the glycogen synthase kinase 3β. Biochem Biophys Res Commun. 249(3), 697-703 (IF=3.322; Ranking=39/72 (Q3); Category: Biophysics) (SCI)
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