論文發表
內容
精準醫學中心論文發表
自2021年至2026年8月，本中心共計發表83篇論文，2026年已發表15篇論文。
NO | 發表年/月 | 發表人 | 研究主題 | 期刊 | Impact factor(2025) |
83 | 2026/8 | 通訊作者：周O志 | Interaction of genetic susceptibility and sunlight exposure on primary open-angle glaucoma risk and progression | Br J Ophthalmol. | SCI(4.5) |
82 | 2026/6 | 第一作者：陳O清 通訊作者：陳O榮 | Predominant HLA class I associations with lupus nephritis susceptibility, histology class and reduced renal function in patients with systemic lupus erythematosus: a retrospective case-control study | Rheumatology Interational | SCI(3.5) |
81 | 2026/6 | 第一作者：于O為 通訊作者：陳O銘 | Genetic polymorphisms associated with therapeutic response and adverse effects to methotrexate in Taiwanese patients with rheumatoid arthritis: a real-world, hospital-based study | Sci Rep. | SCI(4.9) |
80 | 2026/5 | 第一作者：李O庭 通訊作者：陳O銘 | FTO rs7195994 Is associated with TNF inhibitor response in lean rheumatoid arthritis patients: A BMI-stratified pharmacogenetic Analysis | Pharmacogenomics J. | SCI(2.9) |
79 | 2026/5 | 第一作者：張O綱 通訊作者：顏O廷 | Genotype-guided Recall Delineates the Adult Auditory Phenotype in GJB2 p.V37I Homozygotes: High-frequency Vulnerability and Environmental Modulation | Otol Neurotol. | SCI(2.0) |
78 | 2026/5 | 第一作者：陳O清 通訊作者：陳O榮 | Molecular characterization of mammary mucinous cystadenocarcinomareveals recurrent TP53 and RB1 alterations with frequent PI3K–AKTpathway abnormalities | Virchows Archiv | SCI(3.1) |
77 | 2026/5 | 第一作者：江O山 通訊作者：陳O辰 | Female-Specific Risk of TAS2R Variants in Chronic Rhinosinusitis: A Hospital-Based Cohort Study From the Taiwan Precision Medicine Initiative | Int Forum Allergy Rhinol. | SCI(6.8) |
76 | 2026/4 | 第一作者：沈O君 通訊作者：李O儒 | Prognostic Significance of NOTCH3 Small Vessel Disease Staging for the NOTCH3 p.R544C Variant | Neurol Genet. | SCI(4.3) |
75 | 2026/3 | 第一作者：康O庭 | ATP synthasome contributes to efficient energy flux in malignant breast cancer | Mol Cancer. | SCI(42.2) |
74 | 2026/3 | 第一作者：謝O伃 通訊作者：陳O銘 | Candidate pharmacogenetic signals at CCL2 and ITPA associated with JAK inhibitor response in Taiwanese rheumatoid arthritis | Clin Exp Rheumatol | SCI(3.3) |
73 | 2026/2 | 第一作者：林O昇 通訊作者：楊O壹/李O裕 | Liver Steatosis‐Related Polygenic Risk Score Predicts Hepatocellular Carcinoma Risk After Hepatitis C Virus Eradication | Alimentary Pharmacology & Therapeutics | SCI(6.7) |
72 | 2026/1 | 第一作者：林O才 通訊作者：陳O銘 | Additive Association of ABCG2 rs4148155 and SLC22A12 rs75786299 Polymorphisms with Hyperuricemia, Gout, and Nephrolithiasis: A Hospital-Based, Case-Control Study | Kidney Dis (Basel). | SCI(3.1) |
71 | 2026/1 | 第一作者：黃O杰 通訊作者：陳O銘/傅O嫻 | Association Between HLA Alleles and IgA Nephropathy in a Taiwanese Population | Int. J. Mol. Sci. | SCI(4.9) |
70 | 2026/1 | 第一作者：陳O文 通訊作者：陳O銘 | Interactions Between Polygenic Pleiotropy and Air Pollution in the Pathogenesis of Atopic Dermatitis | Dermatitis. | SCI(3.5) |
69 | 2026/1 | 第一作者：花O瑋 通訊作者：顏O廷 | M.827A>G Variant in MT-RNR1 and Its Association With Hearing Loss: A Study in the Taiwanese Adult Population | Otol Neurotol. | SCI(2.0) |
68 | 2025/10 | 第一作者：楊O洲 通訊作者：陳O安 | The Taiwan Precision Medicine Initiative provides a cohort for large-scale studies | Nature | SCI(48.5) |
67 | 2025/10 | 第一作者：傅O慶 通訊作者：許O恒 | Population-specific polygenic risk scores for people of Han Chinese ancestry | Nature | SCI(48.5) |
66 | 2025/10 | 第一作者：張O玲 通訊作者：陳O潔 | Greater lung cancer polygenic risk score in higher air pollution areas linked to greater rate of lung adenocarcinoma: a single-centre study in East Asia | Lung cancer | SCI(4.4) |
65 | 2025/9 | 第一作者：張O琳 通訊作者：陳O旭 | Refining tacrolimus dosing through CYP3A5 pharmacogenetics in Taiwanese renal transplant recipients | Ren Fail. | SCI(3.0) |
64 | 2025/8 | 第一作者：鍾O瑋 通訊作者：陳O銘 | Application of machine learning algorithm for the prediction of lupus nephritis using SNP data, polygenic risk score, and electronic health Record | Health Informatics J. | SCI(2.3) |
63 | 2025/7 | 第一作者：陳O銘 通訊作者：陳O源 | A panel incorporating genetic variants of RIN3, NLRC3,and SLX4 shows promise in predicting remission after tofacitinib therapy in rheumatoid arthritis patients | Clin Exp Rheumatol. | SCI(3.3) |
62 | 2025/7 | 第一作者：陳O潔 通訊作者：朱O文 | Association between high polygenic risk scores and long-term exposure to air pollution in asthma development: a hospital-based case-control study | Environmental Health | SCI(5.9) |
61 | 2025/7 | 第一作者：吳O萱 通訊作者：陳O銘 | Polygenic risk scores of rheumatoid arthritis associated with seropositivity and bone erosions in a Taiwanese population | Scientific Reports | SCI(3.9) |
60 | 2025/7 | 第一作者：周O志 通訊作者：李O儒 | Macular vessel density is associated with cognitive function in preclinical p.R544C NOTCH3 mutation carriers | J Chin Med Assoc. | SCI(2.4) |
59 | 2025/5 | 第一作者：吳O良/張O綱 通訊作者：顏O廷 | KCNQ4 c.546C>G variant is associated with early-onset high-frequency hearing loss, tinnitus,and cardiovascular comorbidities in Taiwanese adults | Scientific Reports | SCI(3.8) |
58 | 2025/3 | 第一作者：鄭O亮 通訊作者：蕭O宏 | Distinct genomic features and mutational signatures of nucleotide excision repair and mismatch repair in thymoma | Am J Cancer Res. | SCI(3.6) |
57 | 2025/3 | 第一作者：王O 通訊作者：宮O帆 | Genetic Variations in CYP19A1 and SLCO1B1 Genes and Their Association with Endometrial Cancer Risk in the Taiwanese Population: A Case-Control Study | Int J Mol Sci. | SCI(4.9) |
56 | 2025/2 | 第一作者：陳O銘/蕭O宏 通訊作者：范O政/林O恒 | Unlocking precision medicine: clinical applications of integrating health records, genetics, and immunology through artificial intelligence | J Biomed Sci. | SCI(12.1) |
55 | 2025/2 | 第一作者：陳O潔 通訊作者：曾O森 | Using a Polygenic Risk Score to Improve the Risk Prediction of Non-Small Cell Lung Cancer in Taiwan | Respirology | SCI(6.3) |
54 | 2025/1 | 第一作者：吳O萱 通訊作者：蕭O宏 | ARTN and CCL23 predicted chemosensitivity in acute myeloid leukemia: an Olink® proteomics approach | Clin Proteomics. | SCI(3.3) |
53 | 2024/12 | 第一作者：林O恩 通訊作者：蕭O宏 | Utilizing Polygenic Risk Score for Breast Cancer Risk Prediction in a Taiwanese population | Int J Med Sci. | SCI(2.3) |
52 | 2024/10 | 第一作者：李O昕 通訊作者：邵O萱 | Using a Polygenic Risk Score to Improve the Risk Prediction of Non-Small Cell Lung Cancer in Taiwan | JCO Precis Oncol. | SCI(5.8) |
51 | 2024/8 | 第一作者：陳O潔 通訊作者：陳O銘 | Interplay between polygenic risk score and solar insolation: Implication for systemic lupus erythematosus diagnosis and pathogenesis | Seminars in Arthritis and Rheumatism | SCI(4.4) |
50 | 2024/8 | 第一作者：李O樺 通訊作者：許O琪/陳O銘 | Association of Methylenetetrahydrofolate Reductase rs1801133 Polymorphism with osteoporosis and fracture risk in Taiwan | Int J Med Sci. | SCI(3.2) |
49 | 2024/7 | 第一作者：王O雋 通訊作者：陳O潔 | Association of HLA alleles with cephalosporin allergy in the Taiwanese population | Sci Rep. | SCI(3.9) |
48 | 2024/7 | 第一作者：梁O閔 通訊作者：陳O銘 | Nailfold capillary measurements correlated to NOTCH3 R544C mutation in preclinical CADASIL patients | JOURNAL OF THE NEUROLOGICAL SCIENCES | SCI(3.2) |
47 | 2024/7 | 第一作者：陳O銘 通訊作者：廖O苓 | tRF-His-GTG-1 enhances NETs formation and interferon-α production in lupus by extracellular vesicle | Cell Communication and Signaling | SCI(8.9) |
46 | 2024/4 | 第一作者：洪O強 通訊作者：蕭O宏 | Polygenic risk score-based prediction of breast cancer risk in Taiwanese women with dense breast using a retrospective cohort study | Sci Rep. | SCI(3.9) |
45 | 2024/4 | 第一作者：陳O如 通訊作者：陳O銘 | Polygenic Risk Score Predicts Earlier-Onset Adult Systemic Lupus Erythematosus and First-Year Renal Diseases in a Taiwanese Cohort | RMD Open | SCI(4.8) |
44 | 2024/2 | 第一作者：李O樺 通訊作者：陳O銘 | The characterization and comorbidities of heterozygous Bardet-Biedl syndrome carriers | Int J Med Sci.. | SCI(3.6) |
43 | 2024/2 | 第一作者：林O正 通訊作者：林O恒 | Association between HNF4A rs1800961 polymorphisms and gallstones in a Taiwanese population. | J Gastroenterol Hepatol. | SCI(4.1) |
42 | 2024/2 | 第一作者：黃O哲 通訊作者：陳O潔 | Polygenic Risk Score in Predicting Esophageal, Oropharyngeal, and Hypopharynx Cancer Risk among Taiwanese Population. | Cancers (Basel) | SCI(5.2) |
41 | 2024/1 | 第一作者：鍾O瑋 通訊作者：陳O銘 | Machine learning approaches to identify systemic lupus erythematosus in anti-nuclear antibody-positive patients using genomic data and electronic health records | BioData Mining | SCI(4.5) |
40 | 2024/1 | 第一作者：廖O苓 通訊作者：陳O銘 | Exosomal microRNAs as biomarkers for viral replication in tofacitinib-treated rheumatoid arthritis patients with hepatitis C
| Sci Rep. | SCI(4.6) |
39 | 2023/12 | 第一作者：張O玲 通訊作者：陳O潔 | Genetic Susceptibility of HLA Alleles to Non-Steroidal Anti-Inflammatory Drug Hypersensitivity in the Taiwanese Population | Biomedicines | SCI(4.7) |
38 | 2023/12 | 第一作者：陳O均 通訊作者：陳O銘 | Utilize polygenic risk score to enhance fracture risk estimation and improve the performance of FRAX in patients with osteoporosis | Arch Osteoporos. | SCI (3.0) |
37 | 2023/10 | 第一作者：邵O宣 通訊作者：陳O銘 | Parental autoimmunity and offspring risks of rheumatic diseases: a nationwide population-based study | Rheumatology | SCI (5.3) |
36 | 2023/10 | 第一作者：江O山 通訊作者：陳O辰 | Risk Prediction of Chronic Rhinosinusitis with or without Nasal Polyps in Taiwanese Population Using Polygenic Risk Score for Nasal Polyps | Biomedicines | SCI (4.7) |
35 | 2023/8 | 第一作者：廖O茹 | CYP2C19 genotypes and osteoporotic fractures in long-term users of proton pump inhibitors: A hospital-based study | Clin Transl Sci. | SCI (3.9) |
34 | 2023/6 | 第一作者：顏O廷 通訊作者：蕭O宏 | GJB2 p.V37I mutation associated with moderate non-syndromic hearing loss in an adult Taiwanese population | Ear and hearing | SCI (3.562) |
33 | 2023/4 | 第一作者：張O霖 | The Prevalence and Features of Medications With Actionable Pharmacogenomic Biomarkers Prescribed to Kidney Transplant Recipients | Transplantation Proceedings | SCI (0.9) |
32 | 2023/3 | 第一作者：顏O茜 通訊作者：陳O銘 | Sex-specific genetic variants associated with adult-onset inguinal hernia in a Taiwanese population | International Journal of Medical Sciences | SCI (3.642) |
31 | 2023/3 | 第一作者：林O才 通訊作者：陳O銘 | The ABCG2 rs2231142 Polymorphism and the Risk of Nephrolithiasis: A Case–Control Study from the Taiwan Biobank | Frontiers in Endocrinology, section Renal Endocrinology | SCI (6.055) |
30 | 2023/2 | 第一作者：石O弘 | Genome-wide association study and identification of systemic comorbidities in development of age-related macular degeneration in a hospital-based cohort of Han Chinese | Front Genet. | SCI (4.772) |
29 | 2023/2 | 第一作者：鄭O亮 通訊作者：滕O林 | Chemoresistance in acute myeloid leukemia: An alternative single-cell RNA sequencing approach | Hematol Oncol. | SCI (4.850) |
28 | 2023/1 | 通訊作者：曾O恩 | Apelin promotes osteosarcoma metastasis by upregulating PLOD2 expression via the Hippo signaling pathway and hsa_circ_0000004/miR-1303 axis | International Journal of Biological Sciences | SCI (10.750) |
27 | 2022/12 | 第一作者：莊O霓 通訊作者：蕭O宏 | Pyuria is associated with dysbiosis of the urinary microbiota in type 2 diabetes patients receiving sodium–glucose cotransporter 2 inhibitors | Microbiology Research | SCI (5.415) |
26 | 2022/11 | 第一作者：曾O恩 | Significant Contribution of Interleukin-18 Genotypes to Childhood Acute Lymphocytic Leukemia Risk in Taiwanese | Anticancer Research | SCI (2.435) |
25 | 2022/11 | 第一作者：林O鴻/莊O霓 | AGR2 expression as a predictive biomarker for therapy response in esophageal squamous cell carcinoma | PLOS One | SCI (3.752) |
24 | 2022/11 | 第一作者：江O山/石O弘 通訊作者：蕭O宏/莊O霓 | Nasal Mycology of Chronic Rhinosinusitis Revealed by Nanopore Sequencing | Diagnostics | SCI (3.992) |
23 | 2022/9 | 第一作者：陳O如 通訊作者：林O文/林O恒 | Prevalence of genetically defined familial hypercholesterolemia and the impact on acute myocardial infarction in Taiwanese population: A hospital-based study | Frontiers in Cardiovascular Medicine | SCI (5.846) |
22 | 2022/9 | 第一作者：江O山 通訊作者：蕭O宏 | Genetic Variations in Bitter and Sweet Taste Receptors in Taiwanese Patients with Chronic Rhinosinusitis | International Forum of Allergy & Rhinology | SCI (5.426) |
21 | 2022/8 | 第一作者：許O忀 通訊作者：洪O廷 | Thiopurine S-Methyltransferase Polymorphisms Predict Hepatotoxicity in Azathioprine-treated Patients with Autoimmune Diseases | J. Personalized Med | SCI (3.508) |
20 | 2022/8 | 第一作者：陳O瑋 通訊作者：陳O銘 | CYP2C19 Loss-of-Function Alleles Predicts Clinical Outcomes in East Asian Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention and Stenting Receiving Clopidogrel | Frontiers in Cardiovascular Medicine
| SCI (5.846) |
19 | 2022/8 | 第一作者：陳O如 通訊作者：陳O銘/蕭O宏 | Single-Cell RNA Sequencing to Decipher the Immunogenicity of ChAdOx1 nCoV-19/AZD1222 and mRNA-1273 Vaccines in Patients with Autoimmune Rheumatic Diseases | Frontiers in Immunology | SCI (8.786) |
18 | 2022/7 | 第一作者：呂O蓉 通訊作者：陳O志 | Perinatal lethal Gaucher disease due to compound heterozygosity of the splicing mutations in GBA gene | Taiwanese Journal of Obstetrics and Gynecology | SCI (1.944) |
17 | 2022/6 | 第一作者：張O綱 通訊作者：陳O潔/蕭O宏 | Impacts of ADH1B and ALDH2 Polymorphisms on Risks of Alcohol-related Disorder and Cancer | Cancer medicine
| SCI (4.711) |
16 | 2022/4 | 第一作者：董O 通訊作者：蕭O宏 | Utilizing Apolipoprotein E genotypes and associated comorbidities for the assessment of the risk for dementia | Frontiers in Aging Neuroscience | SCI (3.562) |
15 | 2022/2 | 第一作者：廖O茹 通訊作者：陳O銘/吳O芬 | Clopidogrel use and CYP2C19 genotypes in patients undergoing vascular intervention procedure: a hospital-based study | Pharmacogenomics and Personalized Medicine | SCI (2.606) |
14 | 2022/1 | 通訊作這：曾O恩 | In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction | Scientific reports | SCI (4.996) |
13 | 2021/12 | 第一作者：鍾O瑋 通訊作者：陳O銘 | Machine Learning Approaches for the Genomic Prediction of Rheumatoid Arthritis and Systemic Lupus Erythematosus | BioData Mining | SCI (4.079) |
12 | 2021/11 | 第一作者：陳O潔 通訊作者：林O恒 | Interaction of alcohol consumption and ABCG2 re2231141 variant contributes to hyperuricemia in a Taiwanese population | JPM | SCI (3.508) |
11 | 2021/10 | 第一作者：顏O廷 通訊作者：陳O銘/江O山 | A KCNQ4 genetic variant associated with late onset non-syndromic hearing loss in a Taiwanese population | Genes | SCI (4.141) |
10 | 2021/10 | 第一作者：孫O軒 通訊作者：蕭O宏 | A Novel Quality-Control Procedure to Improve the Accuracy of Rare Variant Calling in SNP Arrays | Frontier in Genetics | SCI (4.772) |
09 | 2021/10 | 第一作者：洪O廷 | Genomic Sequencing and Functional Analyses Identify MAP4K3/GLK Germline and Somatic Variants Associated with Systemic Lupus Erythematosus | Annals of the rheumatic diseases | SCI (28.003) |
08 | 2021/09 | 第一作者：李O珍/莊O霓 通訊作者：蕭O宏/李O領 | Familial Hypercholesterolemia Genetic Variations and Long-term Cardiovascular Outcomes in Patients with Hypercholesterolemia Who Underwent Coronary Angiography | Genes | SCI (4.141) |
07 | 2021/09 | 第一作者：陳O銘 通訊作者：蕭O宏/林O恒 | Systemic lupus erythematosus and autoimmune features in chronic hospitalized patients with schizophrenia | Schizophrenia Research | SCI (4.662) |
06 | 2021/08 | 第一作者：陳O如 通訊作者：林O恒 | Association of ABCG2 rs2231142 allele and BMI with hyperuricemia in an East Asian population | Frontiers in Genetics | SCI (4.772) |
05 | 2021/07 | 第一作者：董O 通訊作者：蕭O宏 | Characterization of Familial hypercholesterolemia in Taiwanese ischemic stroke patients | Aging | SCI (5.955) |
04 | 2021/06 | 第一作者：洪O廷 | Significant association of ATG16L1 variations with clinical phenotypes of adult-onset Still’s disease | Genes | SCI (4.141) |
03 | 2021/04 | 第一作者：洪O廷 | CARD8 SNP rs11672725 identified as a Potential Genetic Variant for Adult-Onset Still’s Disease | Life (Basel) | SCI (3.253) |
02 | 2021/04 | 第一作者：蕭O宏 通訊作者：滕O林 | Chemoresponse of de novo acute myeloid leukemia to "7+3" induction can be predicted by c-Myc-facilitated cytogenetics | Frontiers in Pharmacology | SCI (5.988) |
01 | 2021/04 | 第一作者：毛O喬/莊O霓 通訊作者：劉O瑜/蕭O宏 | An investigation of conventional microbial culture for the Naja atra bite wound, and the comparison between culture-based 16S Sanger sequencing and 16S metagenomics of the snake oropharyngeal bacterial microbiota | PLOS Neglected Tropical Diseases | SCI (4.781) |