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更新日期 2023/6/29 10:23:33
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  Publications: (* corresponding author) (1993-2023)
 
1 Wang YY, Lin SY, Chang CY, Wu CC, Chen WY, Huang WC, Liao SL, Wang WY, Chen CJ*. 2023. a7 Nicotinic acetylcholine receptor agonist improved brain injury and impaired glucose metabolism in a rat model of ischemic stroke. Metab. Brain Dis. In Press
2 Chang YH, Chang SW, Hsu WT, Yang CP, Lo YL, Chen CJ, Tsai HF, Shiau MY*. 2022. Implication of adipogenesis-coupled CRMP2 functional profile in metabolic homeostasis and imbalance. Biomedicines. 10, 2603
3 Lo YL*, Wang TY, Chen CJ, Chang YH, Lin MY*. 2022. Two-in-One nanoparticle formulation to deliver a tyrosine kinase inhibitor and microRNA for targeting metabolic reprogramming and mitochondrial dysfunction in gastric cancer. Pharmaceutics. 14, 1759.
4 Chen CJ, Wu CC, Chang CY, Li JR, Ou YC, Chen WY, Liao SL, Wang JD*. 2022. Metformin mitigated obesity-driven cancer aggressiveness in tumor-bearing mice. Int. J. Mol. Sci. 23, 9134.
5 Lee CY, Chen SP, Huang-Liu R, Gau SY, Li YC, Chen CJ, Chen WY, Wu CN, Kuan YH*. 2022. Fucoxanthin decreases lipopolysaccharide-induced acute lung injury through the inhibition of RhoA activation and the NF-κB pathway. Environ. Toxicol. 37, 2214-2222.
6 Tzeng CY, Lee WS, Liu KF, Tsou HK, Chen CJ, Peng WH, Tsai JC*. 2022. Allantoin ameliorates amyloid -peptide-induced memory impairment by regulating the PI3K/Akt/GSK-3 signaling pathway in rats. Biomed. Pharmacother. 153, 113389.
7 Wu CC#, Chang CY#, Tzeng CY, Huang JH, Hung CJ, Chen WY, Liao SL, Kuan YH, Chen CJ*. 2022. Preventive intrathecal injection of bupivacaine alleviated microglia activation and neuropathic pain in a rat model of chronic constriction injury. Int. J. Mol. Sci. 23, 7197.
8 Luo CW, Chen SP, Chiang CY, Wu WJ, Chen CJ, Chen WY, Kuan YH*. 2022. Association between ultraviolet B exposure levels and depression in Taiwanese adults: A nested case-control study. Int. J. Environ. Res. Public Health. 19, 6846.
9 Pan PH, Wang YY, Lin SY, Liao SL, Chen YF, Huang WC, Chen CJ*, Chen WY*. 2022. Plumbagin ameliorates bile duct ligation-induced cholestatic liver injury in rats. Biomed. Pharmacother. 151, 113133.
10 Pan PH, Wang YY, Lin SY, Liao SL, Chen YF, Huang WC, Chen CJ*, Chen WY*. 2022. 18b-Glycyrrhetinic acid protects against cholestatic liver injury in bile duct-ligated rats. Antioxidants. 11, 961.
11 Chang CY, Pan PH, Liu TH, Wu CC, Hung CJ, Chen WY, Liao SL, Chen YF, Chen CJ*. 2022. Hyperglycemia augmented neuropathic pain involving the HMGB1/TLR4 inflammatory axis. Tungs’ Medical Journal. 16, 14-22.
12 Chang YH, Yang HY, Chen HW, Hsiao CW, Hsieh YC, Chan YW, Chang SW, Hwang WL, Chen WS, Cheng HH, Chou TY, Chang FP, Ho HL, Chu FY, Lo YL, Chen CJ, Tsai HF, Shiau MY*. 2022. Characterization of collapsing response mediator protein 2 in colorectal cancer progression in subjects with diabetic comorbidity. Cells. 11, 727.
13 Ou YC, Li JR, Wu CC, Yu TM, Chen WY, Liao SL, Kuan YH, Chen YF, Chen CJ*. 2022. Cadmium induces the expression of interleukin-6 through heme oxygenase-1 in HK-2 cells and Sprague-Dawley rats. Food Chem. Toxicol. 161, 112846.
14 Chang CY, Wu CC, Wang JD, Liao SL, Chen WY, Kuan YH, Wang WY, Chen CJ*. 2022. Endoplasmic reticulum stress contributed to dipyridamole-induced impaired autophagic flux and glioma apoptosis. Int. J. Mol. Sci. 23, 579.
15 Cheng TL, Lin ZY, Liao KY, Huang WC, Jhuo CF, Pan PH, Chen CJ, Kuan YH, Chen WY*. 2022. Magnesium lithospermate B attenuates high-fat diet-induced muscle atrophy in C57BL/6J mice. Nutrients. 14, 104.
16 Chiang YW, Su CH, Sun HY, Chen SP, Chen CJ, Chen WY, Chang CC, Chen CM, Kuan YH*. 2022. Bisphenol A induced apoptosis via oxidative stress generation involved Nrf2HO‐1 pathway and mitochondrial dependent pathways in human retinal pigment epithelium (ARPE‐19) cells. Environ. Toxicol. 37, 131-141.
17 Wang YY, Lin SY, Chang CY, Wu CC, Chen WY, Liao SL, Chen YF, Wang WY, Chen CJ*. 2021. Jak2 inhibitor AG490 improved poststroke central and peripheral inflammation and metabolic abnormalities in a rat model of ischemic stroke. Antioxidants. 10, 1958.
18 Tsai PK, Chen SP, Huang-Liu R, Chen CJ, Chen WY, Ng YY, Kuan YH*. 2021. Proinflammatory responses of 1-nitropyrene against RAW264.7 macrophages through Akt phosphorylation and NF-B pathway. Toxics. 9, 276.
19 Chiang YW, Wu SW, Luo CW, Chen SP, Chen CJ, Chen WY, Chang CC, Chen CM, Kuan YH*. 2021. Air pollutant particles, PM2.5, exposure and glaucoma in patients with diabetes: A national population-based nested case-control study. Int. J. Environ. Res. Public Health. 18, 9939.
20 Lin SY, Wang YY, Chang CY, Wu CC, Chen WY, Liao SL, Chen CJ*. 2021. TNF- receptor inhibitor alleviates metabolic and inflammatory changes in a rat model of ischemic stroke. Antioxidants. 10, 851.
21 Chang CY, Pan PH, Wu CC, Liao SL, Chen WY, Kuan YH, Wang WY, Chen CJ*. 2021. Endoplasmic reticulum stress contributes to gefitinib-induced apoptosis in glioma. Int. J. Mol. Sci. 22, 3934.
22 Chang CY, Pan PH, Li JR, Ou YC, Liao SL, Chen WY, Kuan YH, Chen CJ*. 2021. Glycerol improves intracerebral hemorrhagic brain injury and associated kidney dysfunction in Rats. Antioxidants. 10, 623.
23 Huang WC, Liao KY, Hsieh SK, Pan PH, Kuan YH, Liao SL, Chen CJ*, Chen WY*. 2021. Magnesium lithospermate B supplementation improved prenatal bisphenol A exposure-induced metabolic abnormalities in male offspring. Environmental Toxicol. 36, 1932-1943.
24 Chang CY, Wu CC, Wang JD, Li JR, Wang YY, Lin SY, Chen WY, Liao SL, Chen CJ*. 2021. DHA attenuated Japanese Encephalitis Virus infection-induced neuroinflammation and neuronal cell death in cultured rat Neuron/glia. Brain Behav. Immun. 93, 194-205.
25 Sun CY, Li JR, Wang YY, Lin SY, Ou YC, Lin CJ, Wang JD, Liao SL, Chen CJ*. 2021. Indoxyl sulfate caused behavioral abnormality and neurodegeneration in mice with unilateral nephrectomy. Aging US. 13, 6681-6701.
26 Wang JD, Wang YY, Lin SY, Chang CY, Li JR, Huang SW, Chen WY, Liao SL, Chen CJ*. 2021. Exosomal HMGB1 promoted cancer malignancy. Cancers. 13, 877.
27 Sun HY, Luo CW, Chiang YW, Yeh KL, Li YC, Ho YC, Lee SS, Chen WY, Chen CJ, Kuan YH. 2021. Association between PM2.5 exposure level and primary open-angle glaucoma in Taiwanese adults: A nested case-control study. Int. J. Environ. Res. Publ. Health. 18, 1714.
28 Lin CF, Lee SS, Li YC, Ho YC, Chen WY, Chen CJ, Lee MW, Yeh KL, Tsai CS, Huan YH. 2021. Protective effects of Kirenol against lipopolysaccharide-induced acute lung injury through the modulation of the proinflammatory NFB pathway and the AMPK2-/Nrf2-mediated HO-1/AOE pathway. Antioxidants. 10, 204.
29 Liao KY, Chen CJ, Hsieh SK, Pan PH, Chen WY*. 2020. Interleukin-13 ameliorates postischemic hepatic gluconeogenesis and hyperglycemia in rat model of stroke. Metab. Brain Dis. 35, 1201-1210.
30 Jhuo CF, Hsieh SK, Chen CJ, Chen WY*, Tzen JTC*. 2020. Teaghrelin protects SH-SY5Y cells against MPP+-induced neurotoxicity through activation of AMPK/Sirt1/PGC-1 and ERK1/2 pathways. Nutrients. 12, 3665.
31 Li JR, Ou YC, Wu CC, Wang JD, Lin SY, Wang YY, Chen WY, Liao SL, Chen CJ*. 2020. Endoplasmic reticulum stress and autophagy contributed to cadmium nephrotoxicity in HK-2 cells and sprague-dawley rats. Food Chem. Toxicol. 146, 111828.
32 Lin SY, Wang YY, Chang CY, Wu CC, Chen WY, Kuan YH, Liao SL, Chen CJ*. 2020. Effects of -adrenergic blockade on metabolic and inflammatory responses in a rat model of ischemic stroke. Cells. 9, 1373.
33 Lo YL*, Wang CS, Chen YC, Wang TY, Chang YH, Chen CJ, Yang CP. 2020. Mitochondria-directed nanoparticles loaded with a natural compound and a microRNA for promoting cancer cell death via modulation of tumor metabolism and mitochondrial dynamics. Pharmaceutics. 12, 756.
34 Wu CC, Chang CY, Shih KC, Hung CJ, Wang YY, Lin SY, Chen WY, Kuan YH, Liao SL, Wang WY, Chen CJ*. 2020. -Funaltrexamine displayed anti-inflammatory and neuroprotective effects in cells and rodent model of stroke. Int. J. Mol. Sci. 21, 3866.
35 Chang CY, Pan PH, Li JR, Ou YC, Wang JD, Liao SL, Chen WY, Wang WY, Chen CJ*. 2020. Aspirin induced glioma apoptosis through Noxa upregulation. Int. J. Mol. Sci. 21, 4219.
36 Sun CY, Li JR, Wang YY, Lin SY, Ou YC, Lin CJ, Wang JD, Liao SL, Chen CJ*. 2020. P-Cresol sulfate caused behavioral disorders and neurodegeneration in mice with unilateral nephrectomy involving oxidative stress and neuroinflammation. Int. J. Mol. Sci. 21, 6687.
37 Wang YY#, Chang CY#, Lin SY, Wang JD, Wu CC, Chen WY, Kuan YH, Liao SL, Wang WY, Chen CJ*. 2020. Quercetin protects against cerebral ischemia/reperfusion and oxygen glucose deprivation/reoxygenation neurotoxicity. J. Nutr. Biochem. 83, 108436.
38 Wu CC, Hung CJ, Wang YY, Lin SY, Chen WY, KuanYH, Liao SL, Yang CP, Chen CJ*. 2020. Propofol improved glucose tolerance associated with increased FGF-21 and GLP-1 production in male Sprague-Dawley rats. Molecules. 25, 3229.
39 Lin SY, Yang CP, Wang YY, Hsiao CW, Chen WY, Liao SL, Lo YL, Chang YH, Hong CJ, Chen CJ*. 2020. Interleukin-4 improves metabolic abnormalities in leptin-deficient and high-fat diet mice. Int. J. Mol. Sci. 21, 4451.
40 Chen SP, Su CH, Liu RH, Lee MW, Chiang CY, Chen WY, Chen CJ, Wu SW, Kuan YH*. 2020. Protective effect of nerolidol on lipopolysaccharide-induced acute lung injury through the inhibition of NF-kB activation by the reduction of p38 MAPK and JNK phosphorylation. J. Funct. Foods 69, 103943.
41 Wang JD, Chen WY, Li JR, Lin SY, Wang YY, Wu CC, Liao SL, Ko CC, Chen CJ*. 2020. Aspirin mitigated tumor growth in obese mice involving metabolic inhibition. Cells. 9, 569.
42 Tsai PK, Wu SW, Chiang CY, Lee MW, Chen HY, Chen WY, Chen CJ, Yang SF, Yeh CB, Kuan YH*. Evaluation of cytotoxicity, apoptosis, and genotoxicity induced by indium chloride in macrophages through mitochondrial dysfunction and reactive oxygen species generation. Ecotoxicol Environ Saf. 2020 Apr; 193:110348.
43 Wang JD, Chen WY, Li JR, Lin SY, Wang YY, Wu CC, Liao SL, Ko CC, Chen CJ*. Aspirin mitigated tumor growth in obese mice involving metabolic inhibition. Cells. 2020 Feb; 9(3):569.
44 Chang CY, Li JR, Wu CC, Wang JD, Liao SL, Chen WY, Wang WY, Chen CJ*. Endoplasmic reticulum stress contributes to indomethacin-induced glioma apoptosis. Chang and Li equal. Int J Mol Sci. 2020 Jan; 21(2):557.
45 Hsieh SK, Lin HY, Chen CJ, Jhuo CF, Liao KY, Chen WY*, Tzen TC*. Promotion of myotube differentiation and attenuation of muscle atrophy in murine C2C12 myoblast cells treatred with teaghrelin. Chem Biol Interact. 2020 Jan; 315:108893.
46 Tsai SW, Huang CC, Hsu YJ, Chen CJ, Lee PY, Huang YH, Lee MC, Chiu YS, Tung YT*. Accelerated muscle recovery after in vivo curcumin supplementation. Nat Prod Commun. 2020; 15(1):1-9.
47 Ni YL, Shen HT, Su CH, Chen WY, Hung-Liu R, Chen CJ, Chen SP, Kuan YH*. Nerolidol suppresses the inflammatory response during lipopolysaccharide-induced acute lung injury via the modulation of antioxidant enzymes and the AMPK/Nrf-2/HO-1 pathway. Oxid Med Cell Longev. 2019 Nov; 2019:9605980.
48 Ou YC, Li JR, Wang JD, Chang CY, Wu CC, Chen WY, Kuan YH, Liao SL, Lu HC, Chen CJ*. Fibronectin promotes cell growth and migration in human renal cell carcinoma cells. Int J Mol Sci. 2019 Jun; 20(11):2792.
49 Li JR, Ou YC, Wu CC, Wang JD, Lin SY, Wang YY, Chen WY, Chen CJ*. Ischemic preconditioning improved renal ischemia/reperfusion injury and hyperglycemia. IUBMB Life. 2019 Mar; 71(3):321-9.
50 Yang CP, Wang YY, Lin SY, Hong YJ, Liao KY, Hsieh SK, Pan PH, Chen CJ, Chen WY*. Olanzapine induced dysmetabolic changes involving tissue chromium mobilization in female rats. Int J Mol Sci. 2019 Feb; 20(3):640.
51 Li JR, Chiu KY, Ou YC, Wang SS, Chen CS, Yang CK, Ho HC, Cheng CL, Yang CR, Chen CC, Wang SC, Lin CY, Hung SC, Hsu CY, Chen CJ*. Alteration in the serum concentrations of FGF19, FGF21, and FGF23 in patients with urothelial carcinoma. Biofactors. 2019 Jan; 45(1):62-8.
52 Wang WY, Twu CW, Liu YC, Lin HH, Chen CJ*, Lin JC*. Fibronectin promotes nasopharyngeal cancer cell motility and proliferation. Biomed Pharmacother. 2019 Jan; 109:1772-84.
53 Chang CY, Pan PH, Lin SY, Wang YY, Chen WY, Liao SL, Chen CJ*. Comparison of post-ischemic brain injury in young and middle-aged stroke rats. Tungs' Medical Journal (童綜合醫學雜誌) 2019;  13:75-82. (Non-SCI).
54 Chien KJ, Yang ML, Tsai PK, Su CH, Chen CH, Horng CT, Yeh CH, Chen WY, Lin ML, Chen CJ, Chian CY, Kuan YH*. Safrole induced cytotoxicity, DNA damage, and apoptosis in macrophages via reactive oxygen species generation and Akt phosphorylation. Environ Toxicol Pharmacol. 2018 Dec; 64:94-100.
55 Lee CY, Su CH, Tsai PK, Yang ML, Ho YC, Lee SS, Chen CH, Chen WY, Lin ML, Chen CJ, Chian CY, Liu RH, Chang YL, Kuan YH*. Cadmium nitrate-induced neuronal apoptosis is protected by N-acetyl-L-cysteine via reducing reactive oxygen species generation and mitochondrial dysfunction. Biomed Pharmacother. 2018 Dec; 108:448-56.
56 Yang CP, Shiau MY, Lai YR, Ho KT, Hsiao CW, Chen CJ, Lo YL, Chang YH*. Cytokine interleukin-4 boosts insulin-induced energy deposits by enhancing glucose uptake and lipogenesis in hepatocytes. Oxid Med Cell Longev. 2018 Nov; 2018:6923187.
57 Chen WY, Chang CY, Li JR, Wang JD, Wu CC, Kuan YH, Liao SL, Wang WY, Chen CJ*. Anti-inflammatory and neuroprotective effects of fungal immunomodulatory protein involving microglial inhibition. Int J Mol Sci. 2018 Nov; 19(11):3678.
58 Ou YC, Li JR, Wang JD, Chen WY, Kuan YH, Yang CP, Liao SL, Lu HC, Chen CJ*. Aspirin restoresABT-737-mediated apoptosis in human renal carcinoma cells. Biochem Biophys Res Commun. 2018 Jul; 502(2):187-93.
59 Chang CY, Li JR, Wu CC, Wang JD, Yang CP, Chen WY, Wang WW, Chen CJ*. Indomethacin induced glioma apoptosis involving ceramide signals. Exp Cell Res. 2018 Apr; 365(1):66-77.
60 Chang CY, Li JR, Ou YC, Lin SY, Wang YY, Chen WY, Hu YH, Lai CY, Chang CJ, Chen CJ*. Interplay of inflammatory gene expression in pericytes following Japanese encephalitis virus infection. Brain Behav Immun. 2017 Nov; 66:230-43.
61 Wu CC, Hung CJ, Lin SY, Wang YY, Chang CY, Chen WY, Liao SL, Raung SL, Yang CP, Chen CJ*. Treadmill exercise alleviated prenatal buprenorphine exposure-induced depression in rats. Neurochem Int. 2017 Nov; 110:91-100.
62 Lin SY, Wang YY, Chen WY, Liao SL, Chou ST, Yang CP, Chen CJ*. Hepatoprotective activities of rosmarinic acid against extrahepatic cholestasis in rats. Food Chem Toxicol. 2017 Oct; 108(Pt A):214-23.
63 Wang YY, Lin SY, Chen WY, Liao SL, Wu CC, Pan PH, Chou ST, Chen CJ*. Glechoma hederacea extracts attenuate cholestatic liver injury in a bile duct-ligated rat model. J Ethnopharmacol. 2017 May; 204:58-66.
64 Jenkins BJ, Seyssel K, Chiu S, Pan PH, Lin SY, Stanley E,Ament Z, West JA, Summerhill K, Griffin JL, Vetter W, Autio KJ, Hiltunen K, Hazebrouck S, Stepankova R, Chen CJ, Alligier M, Laville M, Moore M, Kraft1 G, Cherrington A, King S, Krauss RM, de Schryver E,Van Veldhoven PP, Ronis M, Koulman A. Odd chain fatty acids; new insights of the relationship between the gut microbiota, dietary intake, biosynthesis and glucose intolerance. Sci Rep. 2017 Mar; 7:44845.
65 Li JR, Wu CC, Chang CY, Ou YC, Lin SY, Wang YY, Chen WY, Raung SL, Liao SL, Chen CJ*. Susceptibility of naïve and differentiated PC12 cells to Japanese encephalitis virus infection. IUBMB Life. 2017 Feb; 69(2):79-87.
66 Sun HL, Peng ML, Lee SS, Chen CJ, Chen WY, Yang ML, Kuan YH*. Endotoxin-induced acute lung injury in mice is protected by 5,7-dihydroxy-8-methoxyflavone via inhibition of oxidative stress and HIF-1α. Environ Toxicol. 2016 Dec; 31(12):1700-9.
67 Chen WY, Mao FC, Liu CH, Kuan YH, Lai NW, Wu CC, Chen CJ*. Chromium supplementation improved post-stroke brain infarction and hyperglycemia. Metab Brain Dis. 2016 Apr; 31(2):289-97.
68 Lin SY, Wang YY, Chuang YH, Chen CJ*. Skeletal muscle proteolysis is associated with sympathetic activation and TNF-α-ubiquitin-proteasome pathway in liver cirrhotic rats. J Gastroenterol Hepatol. 2016 Apr; 31(4):890-6.
69 Huang FM, Chang YC, Lee SS, Yeh CH, Lee KG, Huang YC, Chen CJ, Chen WY, Pan PH, Kuan YH*.  BisGMA-induced cytotoxicity and genotoxicity in macrophages are attenuated by wogonin via reduction of intrinsic caspase pathway activation. Environ Toxicol. 2016 Feb; 31(2):176-84.
70 Chang CY, Li JR, Wu CC, Ou YC, Chen WY, Kuan YH, Wang WY, Chen CJ*. Valproic acid sensitizes human glioma cells to gefitinib-induced autophagy. IUBMB Life. 2015 Nov; 67(11):869-79.
71 Chang CY, Li JR, Chen WY, Ou YC, Lai CY, Hu YH, Wu CC, Chang CJ, Chen CJ*. Disruption of in vitro endothelial barrier integrity by Japanese encephalitis virus-infected astrocytes. Glia. 2015 Nov; 63(11):1915-32.
72 Chang CY, Li JR, Ou YC, Chen WY, Liao SL, Raung SL, Hsiao AL, Chen CJ*. Enterovirus 71 infection caused neuronal cell death and cytokine expression in cultured rat neural cells. IUBMB Life. 2015 Oct; 67(10):789-800.
73 Yeh CH, Shih HC, Hong HM, Lee SS, Yang ML, Chen CJ, Kuan YH*. Protective effect of wogonin on proinflammatory cytokine generation via Jak1/3-STAT1/3 pathway in lipopolysaccharide stimulated BV2 microglial cells. Toxicol Ind Health. 2015 Oct; 31(10):960-6.
74 Chang CY, Kao TK, Chen WY, Ou YC, Li JR, Liao SL, Raung SL, Chen CJ*. Tetramethylpyrazine inhibits neutrophil activation following permanent cerebral ischemia in rats. Biochem Biophys Res Commun. 2015 Jul; 463(3):421-7.
75 Chen CJ, Cheng FC, Su HL, Sheu ML, Lu ZH, Chiang CY, Yang DY, Sheehan J, Pan HC*. Improved neurological outcome by intramuscular injection of human amniotic fluid derived stem cells in a muscle denervation model. PLoS One. 2015 May; 10(5):e0124624.
76 Chang CH, Chan PC, Li JR, Chen CJ, Shieh JJ, Fu YC, Chen HC, Wu MJ*. Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma. Oncotarget. 2015 Jan; 6(3):1478-89.
77 Shen SC, Shen CI, Lin H, Chen CJ, Chang CY, Chen SM, Lee HC, Lai PS, Su HL*. Susceptibility of human embryonic stem cell-derived neural cells to Japanese encephalitis virus infection. PLoS One. 2014 Dec; 9(12):e114990.
78 Lin SY, Wang YY, Chen WY, Chuang YH, Pan PH, Chen CJ*. Beneficial effect of quercetin on cholestatic liver injury. J Nutr Biochem. 2014 Nov; 25(11):1183-95.
79 Chang CY, Kuan YH, Ou YC, Li JR, Wu CC, Pan PH, Chen WY, Huang HY, Chen CJ*. Autophagy contributes to gefitinib-induced glioma cell growth inhibition. Exp Cell Res. 2014 Sep; 327(1):102-12.
80 Yeh CH, Yang ML, Lee CY, Yang CP, Li YC, Chen CJ, Kuan YH*. Wogonin attenuates endotoxin-induced prostaglandin E2 and nitric oxide production via Src-ERK1/2-NFκB pathway in BV-2 microglial cells. Environ Toxicol. 2014 Oct; 29(10):1162-70.
81 Chen WY, Huang YC, Yang ML, Lee CY, Chen CJ, Yeh CH, Pan PH, Horng CT, Kuo WH, Kuan YH*.  Protective effect of rutin on LPS-induced acute lung injury via down-regulation of MIP-2 expression and MMP-9 activation through inhibition of Akt phosphorylation. Int Immunopharmacol. 2014 Oct; 22(2):409-13.
82 Pan PH, Lin SY, Wang YY, Chen WY, Chuang YH, Wu CC, Chen CJ*. Protective effect of rutin on liver injury induced by biliary obstruction in rats. Free Radic Biol Med. 2014 Aug; 73:106-16.
83 Lee CY, Yang JJ, Lee SS, Chen CJ, Huang YC, Huang KH, Kuan YH*. Protective Effect of Ginkgo biloba leaves extract, EGb761, on Endotoxin-Induced Acute Lung Injury via a JNK- and Akt-Dependent NFκB Pathway. J Agric Food Chem. 2014 Jul 9;62(27):6337-44.
84 Ou YC, Li JR, Kuan YH, Raung SL, Wang CC, Hung YY, Pan PH, Lu HC, Chen CJ*. Luteolin sensitizes human 786-O renal cell carcinoma cells to TRAIL-induced apoptosis. Life Sci. 2014 Apr; 100(2):110-7.
85 Wang YY, Lin SY, Chuang YH, Sheu WH, Tung KC, Chen CJ*. Activation of hepatic inflammatory pathways by catecholamines is associated with hepatic insulin resistance in male ischemic stroke rats. Endocrinology. 2014 Apr; 155(4):1235-46. (Equal first author)
86 Wu CC, Hung CJ, Shen CH, Chen WY, Chang CY, Pan HC, Liao SL, Chen CJ*. Prenatal buprenorphine exposure decreases neurogenesis in rats. Toxicol Lett. 2014 Feb; 225(1):92-101.
87 Chen CJ*,Ou YC, Li JR, Chang CY, Pan HC, Lai CY, Liao SL, Raung SL, Chang CJ.2014. Infection of pericytes in vitro by Japanese encephalitis virus disrupts the integrity of endothelial barrier. J Virol. 2014 Jan; 88(2):1150-61.
88 Hung CJ, Wu CC, Chen WY, Chang CY, Kuan YH,Pan HC, Liao SL, Chen CJ*. Depression-like effect of prenatal buprenorphine exposure in rats. PLoS One. 2013 Dec; 8(12):e82262.
89 Chang CY, Kuan YH, Li JR, Chen WY, Ou YC, Pan HC, Liao SL, Raung SL, Chang CJ, Chen CJ*. 2013. Docosahexaenoic acid reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. J Nutr Biochem. 2013 Dec; 24(12):2127-37.
90 Liao SL, Ou YC, Chang CY, Chen WY, Kuan YH, Wang WY, Pan HC, Chen CJ*. Diethylmaleate and iodoacetate in combination caused profound cell death in astrocytes. J Neurochem. 2013 Oct; 127(2):271-82.
91 Kao TK, Chang CY, Ou YC, Chen WY, Kuan YH, Pan HC, Liao SL, Li GZ, Chen CJ*. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp Neurol. 2013 Sep; 247:188-201.
92 Wang YY, Chen CJ, Lin SY, Chuang YH, Sheu WHH,Tung KC*. Hyperglycemia is associated with enhanced gluconeogenesis in a rat model of permanent cerebral ischemia. Mol Cell Endocrinol. 2013 Mar; 367(1-2):50-6.
93 Ou YC, Kuan YH, Li JR, Raung SL, Wang CC, Hung YY, Chen CJ*. Induction of apoptosis by luteolin involving Akt inactivation in human 786-O renal cell carcinoma cells. Evid Based Complement Alternat Med. 2013 Feb; 2013:109105.
94 Lai CY, Ou YC, Chang CY, Pan HC, Chang CJ, Liao SL, Su HL, Chen CJ*. Endothelial Japanese Encephalitis Virus infection enhances migration and adhesion of leukocytes to brain microvascular endothelia via MEK-dependent expression of ICAM1 and the CINC and RANTES chemokines. J Neurochem. 2012 Oct; 123(2):250-61.
95 Yang CP, Wang HA, Tsai TH, Fan A, Hsu CL, Chen CJ, Hong CJ, Chen YM*. Characterization of the neuropsychological phenotype of glycine N-methyltransferase-/- mice and evaluation of its responses to clozapine and sarcosine treatments. Eur Neuropsychopharmacol. 2012 Aug; 22(8):596-606.
96 Hsieh HY, Shieh JJ, Chen CJ, Pan MY, Yang SY, Lin SC, Chang JS, Lee AYL, Chang CC*. Prodigiosin down-regulates SKP2 to induce p27KIP1 stabilization and antiproliferation in human lung adenocarcinoma cells. Br J Pharmacol. 2012 Aug; 166(7):2095-108.
97 Chen WY, Lin SY, Pan HC, Liao SL, Chuang YH, Yen YJ, Lin SY, Chen CJ*. Beneficial effect of docosahexaenoic acid on cholestatic liver injury in rats. J Nutr Biochem. 2012 Mar; 23(3):252-64.
98 Chen CJ*, Ou YC, Chang CY, Pan HC, Liao SL, Chen SY, Raung SL, Lai CY. Glutamate released by Japanese encephalitis virus-infected microglia involves TNF-α signaling and contributes to neuronal death. Glia. 2012 Mar; 60(3):487-501.
99 Tsai SW, Chen CJ*, Chen HL, Chen CM*, Chang YY. Effects of treadmill running on rat gastrocnemius function following botulinum toxin A injection. J Orthop Res. 2012 Feb; 30(2):319-24.
100 Chang CY, Shen CC, Su HL*, Chen CJ*. Gefitinib induces apoptosis in human glioma cells by targeting Bad phosphorylation. J Neurooncol. 2011 Dec; 105(3):507-22.
101 Liao SL, Ou YC, Lin SY, Kao TK, Pan HC, Chang CY, Lai CY, Lu HC, Wang WY, Chen CJ*. Signaling cascades mediate astrocyte death induced by zinc. Toxicol Lett. 2011 Jul; 204(2-3):108-17.
102 Kao TK, Ou YC, Lin SY, Pan HC, Song PJ, Raung SL, Lai CY, Liao SL, Lu HC, Chen CJ*. Luteolin inhibits cytokine expression in endotoxin/cytokine-stimulated microglia. J Nutr Biochem. 2011 Jul; 22(7):612-24.
103 Chen CJ*, Ou YC, Chang CY, Pan HC, Lin SY, Liao SL, Raung SL, Chen SY, Chang CJ. Src signaling involvement in Japanese encephalitis virus-induced cytokine production in microglia. Neurochem Int. 2011 Jul; 58(8):924-33.
104 Pan HC, Sheu ML, Su HL, Chen YJ, Chen CJ, Yang DY, Chiu WT, Cheng FC*. Magnesium supplement promotes sciatic nerve regeneration and down-regulates inflammatory response. Magnes Res. 2011 Jun; 24(2):54-70.
105 Chen CJ*, Ou YC, Chang CY, Pan HC, Liao SL, Raung SL, Chen SY. TNF-a and IL-1b mediate Japanese encephalitis virus-induced RANTES gene expression in astrocytes. Neurochem Int. 2011 Feb; 58(2):234-42. (SCI, IF 3.541, 79/230, Neuroscience)
106 Wang YY, Lin SY*, Chuang YH, Chen CJ, Tung KC, Sheu WHH. Adipose proinflammatory cytokine expression through sympathetic system is associated with hyperglycemia and insulin resistance in a rat ischemic stroke model. Am J Physiol Endocrinol Metab. 2011 Jan; 300(1):E155-63.
107 Chiu WC, Chen CJ, Lee TS, Chen ZJ, Ke PH, Chiang AN*. Oxidative stress enhances AP-1 and NF-kappaB- mediated regulation of beta2-glycoprotein I gene expression in hepatoma cells. J Cell Biochem. 2010 Nov; 111(4):988-98.
108 Chang CY, Ou YC, Kao TK, Pan HC, Lin SY, Liao SL, Wang WY, Lu HC, Chen CJ*. Glucose exacerbates zinc-induced astrocyte death. Toxicol Lett. 2010 Nov; 199(1):102-9.
109 Pan HC, Yang DY, Ou YC, Ho SP, Cheng FC, Chen CJ*. Neuroprotective effect of atorvastatin in an experimental model of nerve crush injury. Neurosurgery. 2010 Aug; 67(2):376-88; discussion 388-9.
110 Chen WY, Chen CJ, Liu CH, Mao FC*. Chromium attenuates high-fat diet-induced nonalcoholic fatty liver disease in KK/HlJ mice. Biochem Biophys Res Commun. 2010 Jul; 397(3):459-64.
111 Lee JP, Li YC, Chen HY, Lin RH, Huang SS, Chen HL, Kuan PC, Liao MF, Chen CJ*, Kuan YH*. Protective effect of luteolin against lipopolysaccharide-induced acute lung injury involves inhibition of MEK/ERK and PI3K/Akt pathways in neutrophils. Acta Pharmacol Sin. 2010 Jul; 31(7):831-8.
112 Lin CH, Chen CJ, Chen CM, Liao SL, Raung SL, Tsai SW*. Treatment of atlantoaxial rotatory fixation with botulinum toxin muscle block and manipulation. J Chin Med Assoc. 2010 Apr; 73(4):222-4.
113 Chen CJ*, Ou YC, Lin SY, Raung SL, Liao SL, Lai CY, Chen SY, Chen JH. Glial activation involvement in neuronal death by Japanese encephalitis virus infection. J Gen Virol. 2010 Apr; 91(Pt 4):1028-37.
114 Wang TM, Chen CJ, Lee TS, Chao HY, Wu WH, Hsieh SC, Sheu HH, Chiang AN*. Docosahexaenoic acid attenuates VCAM-1 expression and NF-κB activation in TNF-α-treated human aortic endothelial cells. J Nutr Biochem. 2011 Feb; 22(2):187-94.
115 Hung CF, Lee CH, Hung SW, Chiu KY, Cheng CL, Yang CR, Chen CJ, Li JR. Invasive adenocarcinoma of the prostate with urethral tumor. J Chin Med Assoc. 2010 Feb; 73(2):101-3.
116 Kao TK, Ou YC, Raung SL, Lai CY, Liao SL, Chen CJ*. Inhibition of nitric oxide production by quercetin in endotoxin/cytokine-stimulated microglia. Life Sci. 2010 Feb; 86(9-10):315-21.
117 Pan PH, Lin SY, Ou YC, Chen WY, Chuang YH, Yen YJ, Liao SL, Raung SL, Chen CJ*. Stearic acid attenuates cholestasis-induced liver injury. Biochem Biophys Res Commun. 2010 Jan; 391(3):1537-42.
118 Kao TK, Ou YC, Raung SL, Chen WY, Yen YJ, Lai CY, Chou ST, Chen CJ*. Graptopetalum paraguayense E. Walther leaves extracts protect against brain injury in ischemic rats. Am J Chin Med. 2010; 38(3):495-516.
119 Pan HC, Kao TK, Ou YC, Yang DY, Yen YJ, Wang CC, Chuang YH, Liao SL, Raung SL, Wu CW, Chiang AN, Chen CJ*. Protective effect of docosahexaenoic acid against brain injury in ischemic rats. J Nutr Biochem. 2009 Sep; 20(9):715-25.
120 Chen WY, Chen CJ, Liao JW, Frank Mao C*. Chromium attenuates hepatic damage in a rat model of chronic cholestasis. Life Sci. 2009 Apr; 84(17-18):606-14.
121 Pan HC, Wu HT, Cheng FC, Chen CH, Sheu ML, Chen CJ*. Potentiation of angiogenesis and regeneration by G-CSF after sciatic nerve crush injury. Biochem Biophys Res Commun. 2009 Apr; 382(1):177-82.
122 Chen WY, Chen CJ, Liu CH, Mao C Frank*. Chromium supplementation enhances insulin signaling in skeletal muscle of obese KK/HlJ diabetic mice. Diabetes Obes Metab. 2009 Apr; 11(4):293-303.
123 Ou YC, Yang CR, Cheng CL, Li JR, Raung SL, Hung YY, Chen CJ*. Indomethacin causes renal epithelial cell injury involving Mcl-1 down-regulation. Biochem Biophys Res Commun. 2009 Mar; 380(3):531-6.
124 Pan HC, Chen CJ, Cheng FC, Ho SP, Liu MJ, Hwang SM, Chang MH, Wang YC. Combination of G-CSF administration and human amniotic fluid mesnchymal stem cell transplsntation promotes peripheral nerve regeneration. Neurochem Res. 2009 Mar; 34(3):518-27.
125 Chang LC, Tsao LT, Chang CS, Chen CJ, Huang LJ, Kuo SC, Lin RH, Wang JP*. Inhibition of nitric oxide production by the carbazole compound LCY-2-CHO via blockade of activator protein-1 and CCAAT/enhancer-binding protein activation in microglia. Biochem Pharmacol. 2008 Aug; 76(4):507-19.
126 Kao TK, Ou YC, Liao SL, Chen WY, Wang CC, Chen SY, Chiang AN, Chen CJ*. Opioids modulate post-ischemic progression in a rat model of stroke. Neurochem Int. 2008 May; 52(6):1256-65.
127 Yang DY, Pan HC, Yen YJ, Wang CC, Chuang YH, Chen SY, Lin SY, Liao SL, Raung SL, Wu CW, Chou MC, Chiang AN, Chen CJ*. Detrimental effects of post-treatment with fatty acids on brain injury in ischemic rats. Neurotoxicology. 2007 Nov; 28(6):1220-9.
128 Raung SL, Chen SY, Liao SL, Chen JH, Chen CJ*. Japanese encephalitis virus infection stimulates Src tyrosine kinase in neuron/glia. Neurosci Lett. 2007 Jun; 419(3):263-8.
129 Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ*. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT. 2007. Eur J Pharmacol. 2007 Jun; 563(1-3):49-60.
130 Liao SL, Ou YC, Chen SY, Chiang AN, Chen CJ*. Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes. Neurochem Int. 2007 Jun; 50(7-8):905-15.
131 Yang DY, Pan HC, Chen CJ, Cheng FC, Wang YC*. Effects of tissue plasminogen activator on cerebral microvessels of rats during focal cerebral ischemia and reperfusion. Neurol Res. 2007 Apr; 29(3):274-82.
132 Chen CJ*, Ou YC, Liao SL, Chen WY, Chen SY, Wu CW, Wang CC, Wang WY, Huang YS, Hsu SH. Transplantation of bone marrow stromal cells for peripheral nerve repair. Exp Neurol. 2007 Mar; 204(1):443-53.
133 Tseng PY, Chen CJ, Sheu CC, Yu CW, Huang YS*. Spontaneous differentiation of adult rat marrow stromal cells in a long-term culture. J Vet Med Sci. 2007 Feb; 69(2):95-102.
134 Chen CJ*, Ou YC, Liao SL, Chen SY, Chen JH. Manganese modulates pro-inflammatory gene expression in activated glia. Neurochem Int. 2006 Jul; 49(1):62-71.
135 Chen CJ*,Ou YC, Lin SY, Liao SL, Huang YS, Chiang AN. L-Glutamate Activates RhoA GTPase Leading to Suppression of Astrocyte Stellation. Eur J Neurosci. 2006 Apr; 23(8):1977-87.
136 Kao TK, Ou YC, Kuo JS, Chen WY, Liao SL, Wu CW, Chen CJ*, Ling NN, Zhang YH, Peng WH. Neuroprotection by tetramethylpyrazine against ischemic brain injury in rats. Neurochem Int. 2006 Feb; 48(3):166-76.
137 Yu CW, Chen CJ, Sheu CC, Tseng PY, Huang YS*. Intracerebroventricular transplantation of marrow stromal cells promotes recovery after spinal cord injury in the rats. Taiwan Vet. J. 2006; 32(3):161-169.
138 Hsu SH*, Chen CY, Lu PS, Lai CS, Chen CJ. Oriented Schwann cell growth on microgrooved surfaces. Biotechnol Bioeng. 2005 Dec; 92(5):579-88.
139 Chang CC, Ou YC, Raung SL, Chen CJ*. Antiviral effect of dehydroepiandrosterone on Japanese encephalitis virus infection. J Gen Virol. 2005 Sep; 86(Pt 9):2513-23.
140 Raung SL, Chen SY, Liao SL, Chen JH, Chen CJ*. Tyrosine kinase inhibitors attenuate Japanese encephalitis virus-induced neurotoxicity. Biochem Biophys Res Commun. 2005 Feb; 327(2):399-406.
141 Chen CJ*, Liao SL, Huang YS, Chiang AN. RhoA inactivation is crucial to manganese-induced astrocyte stellation. Biochem Biophys Res Commun. 2005 Jan; 326(4):873-9.
142 Liao SL, Kao TK, Chen WY, Lin YS, Chen SY, Raung SL, Wu CW, Lu HC, Chen CJ*. Tetramethylpyrazine reduces ischemic brain injury in rats. Neurosci Lett. 2004 Nov; 372(1-2):40-5.
143 Chen CJ*, Chen JH, Chen SY, Liao SL, Raung SL. Up-regulation of RANTES gene expression in neuroglia by Japanese encephalitis virus infection. J Virol. 2004 Nov; 78(22):12107-19.
144 Weng MW, Hsiao YM, Chen CJ, Wang JP, Chen WC, Ko JL*. Benzo[a]pyrene diol epoxide up-regulates COX-2 expression through NF-kappaB in rat astrocytes. Toxicol Lett. 2004 Jul; 151(2):345-55.
145 Chen CJ*, Raung SL, Liao SL, Chen SY. Inhibition of inducible nitric oxide synthase expression by baicalein in endotoxin/cytokine-stimulated microglia. Biochem Pharmacol. 2004 Mar; 67(5):957-65.
146 Liao SL, Chen WY, Raung SL, Chen CJ*. Ethanol attenuates ischemic and hypoxic injury in rat brain and cultured neurons. Neuroreport. 2003 Nov; 14(16):2089-94.
147 Liao SL, Chen CJ*. L-Glutamate decreases glucose utilization by rat cortical astrocytes. Neurosci Lett. 2003 Sep; 348(2):81-4.
148 Liao SL, Chen WY, Raung SL, Chen CJ*. Neuroprotection of naloxone against ischemic injury in rats: role of mu receptor antagonism. Neurosci Lett. 2003 Jul; 345(3):169-72.
149 Chen CJ*, Liao SL. Neurotrophic and neurotoxic effects of zinc on neonatal cortical neuron. Neurochem Int. 2003 May; 42(6):471-9.
150 Chen CJ*, Liao SL. Zinc toxicity on neonatal cortical neurons involvement of glutathione chelation. J Neurochem. 2003 Apr; 85(2):443-53.
151 Liao SL, Chen WY, Chen CJ*. Estrogen attenuates TNF-α expression to provide ischemic neuroprotection in female rats. Neurosci Lett. 2002 Sep; 330(2):159-62.
152 Chen CJ*, Raung SL, Kuo MD, Wang YM. Suppression of Japanese encephalitis virus infection by NSAID. J Gen Virol. 2002 Aug; 83(Pt 8):1897-1905.
153 Chen CJ*, Laio SL. Oxidative stress involves in astrocytic alterations induced by manganese. Exp Neurol. 2002 May; 175(1):216-25.
154 Liao SL, Raung SL, Chen CJ*. Japanese encephalitis virus stimulates superoxide dismutase activity in rat glial cultures. Neurosci Lett. 2002 May; 324(2):133-6.
155 Liao SL, Chen CJ*. Manganese stimulates stellation of cultured rat cortical astrocytes. Neuroreport. 2001 Dec; 12(18):3877-81.
156 Raung SL, Kuo MD, Wang YM, Chen CJ*. Role of reactive oxygen intermediates in Japanese encephalitis virus infection in murine neuroblastoma cells. Neurosci Lett. 2001 Nov; 315(1-2):9-12.
157 Laio SL, Chen CJ*. Tyrosine kinase signaling involved in glutamate-induced astrocyte proliferation. Neuroreport. 2001 Nov;12(16):3519-22.
158 Liao SL, Chen WY, Raung SL, Kuo JS, Chen CJ*. Association of immune responses and ischemic brain infarction in rat. Neuroreport. 2001 Jul; 12(9):1943-7.
159 Chen CJ, Liao SL, Chen WY, Hong JS, Kuo JS*. Cerebral ischemia/reperfusion injury in rat brain: effects of naloxone. Neuroreport. 2001 May; 12(6):1245-9.
160 Liao SL, Chen CJ*. Differential effects of cytokines and redox potential on glutamate uptake in rat cortical glial cultures. Neurosci Lett. 2001 Feb; 299(1-2):113-6.
161 Liao SL, Chen WY, Kuo JS, Chen CJ*. Association of serum estrogen level and ischemic neuroprotection in female rats. Neurosci Lett. 2001 Jan; 297(3):159-62.
162 Chen CJ*, Liao SL, Kuo JS. Gliotoxic action of glutamate on cultured astrocytes. J Neurochem. 2000 Oct; 75(4):1557-65.
163 Chen CJ, Cheng FC, Liao SL, Chen WY, Lin NN, Kuo JS*. Effects of naloxone on lactate, pyruvate metabolism and antioxidant enzyme activity in rat cerebral ischemia/reperfusion. Neurosci Lett. 2000 Jun; 287(2):113-6.
164 Chen CJ*, Liao SL, Kuo MD, Wang YM. Astrocytic alteration induced by Japanese encephalitis virus infection. Neuroreport. 2000 Jun; 11(9):1933-7.
165 Lee CH, Chang SC, Chen CJ, Chang MF*. The nucleolin binding activity of hepatitis delta antigen is associated with nucleolus targeting. J Biol Chem. 1998 Mar; 273(13):7650-6.
166 Chen CJ, Kuo MD, Chien LJ, Hsu SL, Wang YM, Lin JH*. RNA-protein interactions: involvement of NS3, NS5, and 3' noncoding regions of Japanese encephalitis virus genomic RNA. J Virol. 1997 May; 71(5):3466-73.
167 Chang MF*, Chen CH, Lin SL, Chen CJ, Chang SC. Functional domains of delta antigens and viral RNA required for RNA packaging of hepatitis delta virus. J Virol. 1995 Apr; 69(4):2508-14.
168 Chang MF*, Chen CJ, Chang SC. Mutational analysis of delta antigen: effect on assembly and replication of hepatitis delta virus. J Virol. 1994 Feb; 68(2):646-53.
169 Chang MF*, Sun CY, Chen CJ, Chang SC. Functional motifs of delta antigen essential for RNA binding and replication of hepatitis delta virus. J Virol. 1993 May; 67(5):2529-36.
 
 
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