跳到主要內容區塊
Facebook
:::內分泌新陳代謝科 > 部科簡介 > 團隊成員 > 現任成員

林時逸 (新陳代謝科主治醫師)

引用 (4)
轉寄
列印
最後更新時間:2018/10/12 16:21:56
點閱:994

林時逸


現職:
台中榮民總醫院新陳代謝科主治醫師
學經歷:
1. 國立陽明醫學院醫學系畢
2. 國立陽明大學臨床醫學研究所博士
3. 台北榮民總醫院內科部住院醫師 (81/7-84/6)
4. 台北榮民總醫院內科部總醫師  (84/7-87/6)
5. 台中榮民總醫院內科部總醫師  (87/7-88/6)
6. 台中榮民總醫院新陳代謝科主治醫師 (88/7-96/7)
獲獎事蹟︰
99年台中榮民總醫院教學績優主治醫師
專科證書︰
1. 中華民國內科專科醫師 (84/10)
2. 中華民國內分泌新陳代謝專科醫師  (86/08)
3. 中華民國糖尿病衛教師 (89/01)
專科學會︰
1. 中華民國內科學會
2. 中華民國內分泌學會
3. 中華民國糖尿病學會
4. 中華民國糖尿病衛教學會
專長︰
1. 老鼠甲狀腺細胞培養,人類眼球纖維母細胞培養
2. 分子生物技術: northern blotting,southern blotting, tissue RNA DNA extraction, PCR, protein dialysis
3. Thyroid sonography, fine needle aspiration cytology
4. 一般內科學,內分泌學,糖尿病學
研究計劃
1. 脂肪酸抗肝纖維化活性分析. 院內計劃 980101-981231.
2. 內毒素在高脂飲食誘發肥胖鼠之胰臟胰島發炎機轉之探討區. 榮台聯大 980101-981231.
3. 肝硬化骨骼肌肉細胞凋亡研究 (三年期計劃). 國科會 960801-990731.
4. 探討壓力性高血糖的生物意義及變化機制99-2314-B-075A-003-MY3 總執行期限:99/08/01-102/07/31(新制多年期)
5. 探討芸香素膽汁鬱積肝損傷保護活性. 院內計劃 1000101-1001231.
6. 兒童期、青少年期與成年期使用高脂肪誘發肥胖小鼠對於成年時糖分代謝與脂肪組織發炎細胞激素改變之探討. 院內計劃 1010101-1011231.
著作及研究︰
期刊論文 (Corresponding*)
1. Lin SY, Sheu WH, Lee WJ, Song YM, Chen YT. Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is associated with increased plasma leptin levels in obese Chinese women. Zhonghua Yi Xue Za Zhi (Taipei). 1999 Sep;62(9):569-76.
2. Sheu WH, Jeng CY, Lee WJ, Lin SY, Pei D, Chen YT. Simvastatin treatment on postprandial hypertriglyceridemia in type 2 diabetes mellitus patients with combined hyperlipidemia. Metabolism. 2001 Mar;50(3):355-9.
3. Chao CS, Lin SY, Sheu WH. Graves' disease presented as painful goiter. Horm Res. 2002;57(1-2):53-6.
4. Lee IT, Lin SY, Sheu WH. Serial body composition by bioimpedance analysis in a diabetic subject with rapid insulin-induced weight gain--a case report. Kaohsiung J Med Sci. 2002 Jan;18(1):45-8.
5. Lin SY, Sheu WH, Chang MC, Tang KT, Lee TI, Lin HD. Diagnosis of thyroid metastasis in cancer patients with thyroid mass by fine needle aspiration cytology and ultrasonography. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Mar;65(3):101-5.
6. Chao CS, Lin SY, Sheu WH, Ho WL. Thyroglossal duct cyst with papillary carcinoma. Zhonghua Yi Xue Za Zhi (Taipei). 2002 Apr;65(4):183-6.
7. Lin SY, Wang YY, Sheu WH. Increased serum leptin concentrations correlate with soluble tumour necrosis factor receptor levels in patients with cirrhosis. Clin Endocrinol (Oxf). 2002 Dec;57(6):805-11.
8. Lee IT, Sheu WH, Lin SY, Lee WJ, Song YM, Liu HC. Simvastatin reduces plasma concentration of high-sensitivity C-reactive protein in type 2 diabetic patients with hyperlipidemia. J Diabetes Complications. 2002 Nov-Dec;16(6):382-5.
9. Lee IT, Sheu WH, Lin SY. Hypoglycemia probably due to accidental intake of repaglinide. Chang Gung Med J. 2002 Nov;25(11):783-6.
10. Lee IT, Sheu WH, Lin SY. Familial form of thyroid dysgenesis: report of thyroid hemiagenesis with accompanying Graves' disease in a woman whose daughter has thyroid agenesis. Horm Res. 2003;59(1):47-9.
11. Lin SY, Wang YY, Sheu WH. Preoperative plasma concentrations of vascular endothelial growth factor and matrix metalloproteinase 9 are associated with stage progression in papillary thyroid cancer. Clin Endocrinol (Oxf). 2003 Apr;58(4):513-8.
12. Lee IT, Lin SY, Sheul WH. Mood disorder and secondary adrenal insufficiency after pituitary tumor operation and radiotherapy. J Chin Med Assoc. 2003 Jun;66(6):375-8.
13. Lee IT, Sheu WH, Liau YJ, Lin SY, Lee WJ, Lin CC. Relationship of stressful life events, anxiety and depression to hyperthyroidism in an asian population. Horm Res. 2003;60(5):247-51.
14. Tai TS, Lin SY, Sheu WH. Metabolic effects of growth hormone therapy in an Alström syndrome patient. Horm Res. 2003;60(6):297-301.
15. Lin SY, Wang YY, Sheu WH. Increased serum soluble tumor necrosis factor receptor levels are associated with insulin resistance in liver cirrhosis. Metabolism. 2004 Jul;53(7):922-6.
16. Lin SY, Chen WY, Lee FY, Huang CJ, Sheu WH. Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-alpha. Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E493-501.
17. Lin SY, Sheu WH, Chen WY, Lee FY, Huang CJ. Stimulated resistin expression in white adipose of rats with bile duct ligation-induced liver cirrhosis: relationship to cirrhotic hyperinsulinemia and increased tumor necrosis factor-alpha. Mol Cell Endocrinol. 2005 Mar 31;232(1-2):1-8.
18. Lin SY, Chen WY, Chiu YT, Lee WJ, Wu HS, Sheu WH. Different tumor necrosis factor-alpha-associated leptin expression in rats with dimethylnitrosamine and bile duct ligation-induced liver cirrhosis. Metabolism. 2005 Apr;54(4):445-52.
19. Wang YY, Lin SY, Lai WA, Liu PH, Sheu WH. Association between adenomas of rectosigmoid colon and metabolic syndrome features in a Chinese population. J Gastroenterol Hepatol. 2005 Sep;20(9):1410-5.
20. Lin SY, Wang YY, Liu PH, Lai WA, Sheu WH. Lower serum free thyroxine levels are associated with metabolic syndrome in a Chinese population. Metabolism. 2005 Nov;54(11):1524-8.
21. Chiou JB, Lin SY, Yen CH, Sheu WH, Jeng CY. Efficacy and safety of a mixture of two different brands of insulin products in patients with type 1 diabetes mellitus. J Chin Med Assoc. 2005 Nov;68(11):517-21.
22. Lin SY, Sheu WH. An emerging link between insulin resistance and inflammation. J Chin Med Assoc. 2006 Jun;69(6):245-7.
23. Lin H, Chen MC, Chiu CY, Song YM, Lin SY. Cdk5 regulates STAT3 activation and cell proliferation in medullary thyroid carcinoma cells. J Biol Chem. 2007 Feb 2;282(5):2776-84.
24. Wu MC, Lee WJ, Tschen SM, Lin SY, Lee IT, Jeng CY, Tseng LN, Liu YM, Chen BY, Sheu WH. Predictors of mortality in hospitalized diabetic patients: A 7-year prospective study. Diabetes Res Clin Pract. 2008 Jun;80(3):449-54.
25. Huang SC, Wu VC, Lin SY, Sheu WH, Song YM, Lin YH, Wu CC, Chang WD. Factors related to clinical hypothyroid severity in thyroid cancer patients after thyroid hormone withdrawal. Thyroid. 2009 Jan;19(1):13-20.
26. Wang JS, Lin SY, Sheu WH, Lee IT, Tseng LN, Song YM. Diabetes Res Clin Pract. Effects of patient volume on quality of outpatient diabetes care. 2009 May;84(2):e27-9.
27. Lee WJ, Ou HC, Wu CM, Lee IT, Lin SY, Lin LY, Tsai KL, Lee SD, Sheu WH. Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein. J Agric Food Chem. 2009 Dec 9;57(23):11406-17.
28. Wang YY, Lin SY*, Sheu WH, Liu PH, Tung KC. Obesity and diabetic hyperglycemia were associated with serum alanine aminotransferase activity in patients with hepatitis B infection. Metabolism. 2010 Apr;59(4):486-91. Epub 2009 Oct 20.
29. Wang YY, Lin SY*, Chuang YH, Mao CH, Tung KC, Sheu WH. Protein nitration is associated with increased proteolysis in skeletal muscle of bile duct ligation-induced cirrhotic rats. Metabolism. 2010 Apr;59(4):468-72. Epub 2009 Oct 20.
30. Lee WJ, Ou HC, Wu CM, Lee IT, Lin SY, Lin LY, Tsai KL, Lee SD, Sheu WH. Sesamin mitigates inflammation and oxidative stress in endothelial cells exposed to oxidized low-density lipoprotein. J Agric Food Chem. 2009 Dec 9;57(23):11406-17.
31. Lin SY, Huang SC, Sheu WH. Circulating adiponectin concentrations were related to free thyroxine levels in thyroid cancer patients after thyroid hormone withdrawal. Metabolism. 2010 Feb;59(2):195-9. Epub 2009 Sep 17.
32. Pan PH, Lin SY, Ou YC, Chen WY, Chuang YH, Yen YJ, Liao SL, Raung SL, Chen CJ. Stearic acid attenuates cholestasis-induced liver injury. Biochem Biophys Res Commun. 2010 Jan 15;391(3):1537-42.
33. Wang YY, Lin SY*, Chuang YH, Chen CJ, Tung KC, Sheu WH. Adipose proinflammatory cytokine expression through sympathetic system is associated with hyperglycemia and insulin resistance in a rat ischemic stroke model. Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E155-63. Epub 2010 Oct 26.
34. Wang JS, Tu ST, Lee IT, Lin SD, Lin SY, Su SL, Lee WJ, Sheu WH. Contribution of postprandial glucose to excess hyperglycaemia in Asian type 2 diabetic patients using continuous glucose monitoring. Diabetes Metab Res Rev. 2011 Jan;27(1):79-84. doi: 10.1002/dmrr.1149. Epub 2010 Nov 10.
35.Gkrania-Klotsas E, Ye Z, Cooper AJ, Sharp SJ, Luben R, Biggs ML, Chen LK, Gokulakrishnan K, Hanefeld M, Ingelsson E, Lai WA, Lin SY, Lind L, Lohsoonthorn V, Mohan V, Muscari A, Nilsson G, Ohrvik J, Chao Qiang J, Jenny NS, Tamakoshi K, Temelkova-Kurktschiev T, Wang YY, Yajnik CS, Zoli M, Khaw KT, Forouhi NG, Wareham NJ, Langenberg C. Differential White Blood Cell Count and Type 2 Diabetes: Systematic Review and Meta-Analysis of Cross-Sectional and Prospective Studies. PLoS One. 2010 Oct 18;5(10):313405.
36.Wang JS, Tu ST, Lee IT, Lin SD, Lin SY, Su SL, Lee WJ, Sheu WH. Contribution of postprandial glucose to excess hyperglycaemia in Asian type 2 diabetic patients using continuous glucose monitoring. Diabetes Meta Res Rev. 2011 Jan;27(1);79-84.
37.Liang KW, Lee WJ, Lee IT, Lee WL, Lin SY, Hsu SL, Wan CJ, Yu CY, Tsai IC, Fu CP, Ting CT, Sheu WH. Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome. Clin Chim Acta. 2011 Sep 18;412(19020):1835-41.
38.Lin SD, Wang JS, Hsu SR, Sheu WH, Tu ST, Lee IT, Su SL, Lin SY, Wang SY, Hsieh MC. The beneficial effect of α-glucosidase inhibitor on glucose variability compared with sulfonylurea in Taiwanese type 2 diabetic patients inadequately controlled with metformin: preliminary data. J Diabetes Complications. 2011 Sep-Oct;25(5):332-8.
39.Wang JS, Lin SD, Lee WJ, Su SL, Lee IT, Tu ST, Tseng YH, Lin SY, Sheu WH. Effects of acarbose versus glibenclamide on glycemic excursion and oxidative stress in type 2 diabetic patients inadequately controlled by metformin: a 24-week, randomized, open-label, parallel-group comparison. Clin Ther. 2011 Dec;33(12):1932-42.
會議論文
1. The control of dyslipidemia and use of lipid lowering drugs among patients with type 2 diabetes in a medical center in central Taiwan. 98年中華民國內分泌暨糖尿病學會年會.